Cell Biology Antibodies 7

Anti-CACNA1B Antibody (CAB16687)

(No reviews yet) Write a Review
SKU:
CAB16687
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-CACNA1B Antibody
Antibody SKU:CAB16687
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 2200 to the C-terminus of human CACNA1B (NP_000709.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:U-87MG
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 2200 to the C-terminus of human CACNA1B (NP_000709.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:SITY KTAN SSPI HFAG AQTS LPAF SPGR LSRG LSEH NALL QRDP LSQP LAPG SRIG SDPY LGQR LDSE ASVH ALPE DTLT FEEA VATN SGRS SRTS YVSS LTSQ SHPL RRVP NGYH CTLG LSSG GRAR HSYH HPDQ DHWC
Gene ID:774
Uniprot:Q00975
Cellular Location:
Calculated MW:251kDa/262kDa
Observed MW:262kDa
Synonyms:CACNA1B, BIII, CACNL1A5, CACNN, Cav2.2, DYT23
Background:The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene.
NCBI Summary:The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
UniProt Code:Q00975
NCBI GenInfo Identifier:4502523
NCBI Gene ID:774
NCBI Accession:NP_000709
UniProt Related Accession:Q00975
Molecular Weight:Predicted Molecular Mass: 25.1kDaAccurate Molecular Mass: 28kDa
NCBI Full Name:voltage-dependent N-type calcium channel subunit alpha-1B isoform 1
NCBI Synonym Full Names:calcium voltage-gated channel subunit alpha1 B
NCBI Official Symbol:CACNA1B  
NCBI Official Synonym Symbols:BIII; CACNN; DYT23; Cav2.2; NEDNEH; CACNL1A5  
NCBI Protein Information:voltage-dependent N-type calcium channel subunit alpha-1B
UniProt Protein Name:Voltage-dependent N-type calcium channel subunit alpha-1B
UniProt Synonym Protein Names:Brain calcium channel III; BIII; Calcium channel, L type, alpha-1 polypeptide isoform 5; Voltage-gated calcium channel subunit alpha Cav2.2
Protein Family:GTP-binding protein
UniProt Gene Name:CACNA1B  
UniProt Entry Name:CAC1B_HUMAN
Anti-CACNA1B Antibody (CAB16687)Western blot analysis of extracts of U-87MG cells, using CACNA1B antibody (CAB16687) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 3min.
View AllClose

0 Reviews

View AllClose

Related Products