Cell Biology Antibodies 9

Anti-CA14 Antibody (CAB4573)

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SKU:
CAB4573
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
CA14
Synonyms:
CAXiV
Research Area:
Cell Biology

Description

Product Name:CA14 Rabbit pAb
Product Code:CAB4573
Size:20uL, 50uL, 100uL
Synonyms:CA14, CAXiV
Applications:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 16-290 of human CA14 (NP_036245.1).
Applications:WB
Recommended Dilutions:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:U-937, M21, Jurkat, A375, Mouse lung
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 16-290 of human CA14 (NP_036245.1).
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:ADGG QHWT YEGP HGQD HWPA SYPE CGNN AQSP IDIQ TDSV TFDP DLPA LQPH GYDQ PGTE PLDL HNNG HTVQ LSLP STLY LGGL PRKY VAAQ LHLH WGQK GSPG GSEH QINS EATF AELH IVHY DSDS YDSL SEAA ERPQ GLAV LGIL IEVG ETKN IAYE HILS HLHE VRHK DQKT SVPP FNLR ELLP KQLG QYFR YNGS LTTP PCYQ SVLW TVFY RRSQ ISME QLEK LQGT LFST EEEP SKLL VQNY RALQ PLNQ RMVF ASFI QAGS SYTT GEM
Gene ID:23632
Uniprot:Q9ULX7
Cellular Location:Membrane, Single-pass type I membrane protein
Calculated MW:37kDa
Observed MW:50kDa
UniProt Protein Function:CA14: Reversible hydration of carbon dioxide. Belongs to the alpha-carbonic anhydrase family.
UniProt Protein Details:

Protein type:Energy Metabolism - nitrogen; Membrane protein, integral; Lyase; EC 4.2.1.1

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: integral to membrane; plasma membrane

Molecular Function:carbonate dehydratase activity; metal ion binding

Biological Process: bicarbonate transport

NCBI Summary:Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XIV is predicted to be a type I membrane protein and shares highest sequence similarity with the other transmembrane CA isoform, CA XII; however, they have different patterns of tissue-specific expression and thus may play different physiologic roles. [provided by RefSeq, Jul 2008]
UniProt Code:Q9ULX7
NCBI GenInfo Identifier:8928036
NCBI Gene ID:23632
NCBI Accession:Q9ULX7.1
UniProt Secondary Accession:Q9ULX7,Q5TB24, Q8NCF4,
UniProt Related Accession:Q9ULX7
Molecular Weight:337
NCBI Full Name:Carbonic anhydrase 14
NCBI Synonym Full Names:carbonic anhydrase XIV
NCBI Official Symbol:CA14  
NCBI Official Synonym Symbols:CAXiV  
NCBI Protein Information:carbonic anhydrase 14; CA-XIV; carbonic dehydratase; carbonate dehydratase XIV
UniProt Protein Name:Carbonic anhydrase 14
UniProt Synonym Protein Names:Carbonate dehydratase XIV; Carbonic anhydrase XIV; CA-XIV
Protein Family:Carbonic anhydrase
UniProt Gene Name:CA14  
UniProt Entry Name:CAH14_HUMAN
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