Cell Biology Antibodies 1
Anti-BTN2A1 Antibody (CAB10418)
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- SKU:
- CAB10418
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-BTN2A1 Antibody |
| Antibody SKU: | CAB10418 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-240 of human BTN2A1 (NP_510961.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | U-251MG, HT-1080, HT-29, LO2, A-549, 293T |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-240 of human BTN2A1 (NP_510961.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | FIVV GPTD PILA TVGE NTTL RCHL SPEK NAED MEVR WFRS QFSP AVFV YKGG RERT EEQM EEYR GRTT FVSK DISR GSVA LVIH NITA QENG TYRC YFQE GRSY DEAI LHLV VAGL GSKP LISM RGHE DGGI RLEC ISRG WYPK PLTV WRDP YGGV APAL KEVS MPDA DGLF MVTT AVII RDKS VRNM SCSI NNTL LGQK KESV IFIP ESF |
| Gene ID: | 11120 |
| Uniprot: | Q7KYR7 |
| Cellular Location: | Membrane, Single-pass type I membrane protein |
| Calculated MW: | 37kDa/42kDa/53kDa/59kDa/60kDa |
| Observed MW: | 72kDa |
| Synonyms: | BTN2A1, BK14H9.1, BT2.1, BTF1, BTN2.1, DJ3E1.1 |
| Background: | This gene encodes a member of the immunoglobulin superfamily. The gene is located in a cluster of butyrophilin-like genes in the juxta-telomeric region of the major histocompatibility complex on chromosome 6. A pseudogene of this gene has been identified in this cluster. The encoded protein is an integral plasma membrane protein involved in lipid, fatty-acid, and sterol metabolism. Alterations in this gene may be associated with several disease states including metabolic syndrome. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | BTN2A1: a member of the BTN2 subfamily of genes, which encode proteins belonging to the butyrophilin protein family. The gene is located in a cluster on chromosome 6, consisting of seven genes belonging to the expanding B7/butyrophilin-like group, a subset of the immunoglobulin gene superfamily. The encoded protein is an integral plasma membrane B box protein involved in lipid, fatty-acid and sterol metabolism. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010] |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 6p22.1 Cellular Component: integral to plasma membrane Biological Process: lipid metabolic process |
| NCBI Summary: | This gene encodes a member of the immunoglobulin superfamily. The gene is located in a cluster of butyrophilin-like genes in the juxta-telomeric region of the major histocompatibility complex on chromosome 6. A pseudogene of this gene has been identified in this cluster. The encoded protein is an integral plasma membrane protein involved in lipid, fatty-acid, and sterol metabolism. Alterations in this gene may be associated with several disease states including metabolic syndrome. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013] |
| UniProt Code: | Q7KYR7 |
| NCBI GenInfo Identifier: | 215274180 |
| NCBI Gene ID: | 11120 |
| NCBI Accession: | Q7KYR7.3 |
| UniProt Secondary Accession: | Q7KYR7,O00475, P78408, Q59EN4, Q7KYQ7, Q7Z386, Q96AV7 Q9NU62, B4DLP9, E9PGR4, |
| UniProt Related Accession: | Q7KYR7 |
| Molecular Weight: | 527 |
| NCBI Full Name: | Butyrophilin subfamily 2 member A1 |
| NCBI Synonym Full Names: | butyrophilin, subfamily 2, member A1 |
| NCBI Official Symbol: | BTN2A1 |
| NCBI Official Synonym Symbols: | BTF1; BT2.1; BTN2.1; DJ3E1.1; BK14H9.1 |
| NCBI Protein Information: | butyrophilin subfamily 2 member A1 |
| UniProt Protein Name: | Butyrophilin subfamily 2 member A1 |
| Protein Family: | Butyrophilin subfamily |
| UniProt Gene Name: | BTN2A1 |
| UniProt Entry Name: | BT2A1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using BTN2A1 antibody (CAB10418) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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