Cell Biology Antibodies 1

Anti-BTN1A1 Antibody (CAB10107)

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SKU:
CAB10107
Product Type:
Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-BTN1A1 Antibody
Antibody SKU:CAB10107
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 27-210 of human BTN1A1 (NP_001723.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse, Rat
Positive Samples:Mouse liver, Rat liver
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 27-210 of human BTN1A1 (NP_001723.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:APFD VIGP PEPI LAVV GEDA ELPC RLSP NASA EHLE LRWF RKKV SPAV LVHR DGRE QEAE QMPE YRGR ATLV QDGI AKGR VALR IRGV RVSD DGEY TCFF REDG SYEE ALVH LKVA ALGS DPHI SMQV QENG EICL ECTS VGWY PEPQ VQWR TSKG EKFP STSE SRNP DEEG LFTV AASV IIRD
Gene ID:696
Uniprot:Q13410
Cellular Location:Membrane, Secreted, Single-pass type I membrane protein
Calculated MW:58kDa
Observed MW:59kDa
Synonyms:BTN1A1, BT, BTN, BTN1
Background:Butyrophilin is the major protein associated with fat droplets in the milk. It is a member of the immunoglobulin superfamily. It may have a cell surface receptor function. The human butyrophilin gene is localized in the major histocompatibility complex (MHC) class I region of 6p and may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families
UniProt Protein Function:May function in the secretion of milk-fat droplets. May act as a specific membrane-associated receptor for the association of cytoplasmic droplets with the apical plasma membrane. Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.
NCBI Summary:Butyrophilin is the major protein associated with fat droplets in the milk. It is a member of the immunoglobulin superfamily. It may have a cell surface receptor function. The human butyrophilin gene is localized in the major histocompatibility complex (MHC) class I region of 6p and may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families [provided by RefSeq, Jul 2008]
UniProt Code:Q13410
NCBI GenInfo Identifier:166197658
NCBI Gene ID:696
NCBI Accession:NP_001723.2
UniProt Secondary Accession:Q13410,Q4VAN3, Q4VAN4, Q9H458,
UniProt Related Accession:Q13410
Molecular Weight:22.5kDa
NCBI Full Name:butyrophilin subfamily 1 member A1
NCBI Synonym Full Names:butyrophilin subfamily 1 member A1
NCBI Official Symbol:BTN1A1  
NCBI Official Synonym Symbols:BT; BTN; BTN1  
NCBI Protein Information:butyrophilin subfamily 1 member A1
UniProt Protein Name:Butyrophilin subfamily 1 member A1
Protein Family:Early activation antigen
UniProt Gene Name:BTN1A1  
Anti-BTN1A1 Antibody (CAB10107)Western blot analysis of extracts of various cell lines, using BTN1A1 antibody (CAB10107) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
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system_update_altDatasheetMouse BTN1A1 Recombinant Protein Mouse Butyrophilin subfamily 1 member A1(BTN1A1) is a type I transmembrane glycoprotein which is a member of the Ig superfamily. The BTN