Immunology Antibodies 1
Anti-BTLA Antibody (CAB13449)
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- SKU:
- CAB13449
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Description
| Antibody Name: | Anti-BTLA Antibody |
| Antibody SKU: | CAB13449 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 31-241 of human BTLA (NP_001078826.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | Jurkat, Mouse spleen, Mouse thymus |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 31-241 of human BTLA (NP_001078826.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | KESC DVQL YIKR QSEH SILA GDPF ELEC PVKY CANR PHVT WCKL NGTT CVKL EDRQ TSWK EEKN ISFF ILHF EPVL PNDN GSYR CSAN FQSN LIES HSTT LYVT GKQN ELSD TAGR EINL VDAH LKSE QTEA STRQ NSQV LLSE TGIY DNDP DLCF RMQE GSEV YSNP CLEE NKPG IVYA SLNH SVIG PNSR LARN VKEA PTEY ASIC VRS |
| Gene ID: | 151888 |
| Uniprot: | Q7Z6A9 |
| Cellular Location: | Membrane, Single-pass type I membrane protein |
| Calculated MW: | 27kDa/32kDa |
| Observed MW: | 33kDa |
| Synonyms: | BTLA, BTLA1, CD272 |
| Background: | This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis. |
| UniProt Protein Function: | Lymphocyte inhibitory receptor which inhibits lymphocytes during immune response. |
| NCBI Summary: | This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis. [provided by RefSeq, Aug 2011] |
| UniProt Code: | Q7Z6A9 |
| NCBI GenInfo Identifier: | 296439425 |
| NCBI Gene ID: | 151888 |
| NCBI Accession: | Q7Z6A9.3 |
| UniProt Secondary Accession: | Q7Z6A9,Q3B831, Q3HS85, Q6ZNH9, |
| UniProt Related Accession: | Q7Z6A9 |
| Molecular Weight: | 27,317 Da |
| NCBI Full Name: | B- and T-lymphocyte attenuator |
| NCBI Synonym Full Names: | B and T lymphocyte associated |
| NCBI Official Symbol: | BTLA |
| NCBI Official Synonym Symbols: | BTLA1; CD272 |
| NCBI Protein Information: | B- and T-lymphocyte attenuator |
| UniProt Protein Name: | B- and T-lymphocyte attenuator |
| UniProt Synonym Protein Names: | B- and T-lymphocyte-associated protein; CD_antigen: CD272 |
| Protein Family: | B- and T-lymphocyte attenuator |
| UniProt Gene Name: | BTLA |
 | Western blot analysis of extracts of various cell lines, using BTLA antibody (CAB13449) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
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