Cell Biology Antibodies 14

Anti-BRPF1 Antibody (CAB17012)

(No reviews yet) Write a Review
SKU:
CAB17012
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-BRPF1 Antibody
Antibody SKU:CAB17012
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human BRPF1 (NP_001003694).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:Mouse testis
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human BRPF1 (NP_001003694).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MGVD FDVK TFCH NLRA TKPP YECP VETC RKVY KSYS GIEY HLYH YDHD NPPP PQQT PLRK HKKK GRQS RPAN KQSP SPSE VSQS PGRE VMSY AQAQ RMVE VDLH GRVH RISI FDNL DVVS EDEE APEE APEN GSNK ENTE TPAA TPKS GKHK NKEK RKDS NHHH HHNV SAST TPKL PEVV YREL EQDT PDAP PRPT SYYR
Gene ID:7862
Uniprot:P55201
Cellular Location:
Calculated MW:
Observed MW:151kDa
Anti-BRPF1 Antibody (CAB17012)Western blot - BRPF1 Rabbit pAb (CAB17012)
Synonyms:BRPF1, BR140, IDDDFP, peregrin
Background:This gene encodes a bromodomain, PHD finger and chromo/Tudor-related Pro-Trp-Trp-Pro (PWWP) domain containing protein. The encoded protein is a component of the MOZ/MORF histone acetyltransferase complexes which function as a transcriptional regulators. This protein binds to the catalytic MYST domains of the MOZ and MORF proteins and may play a role in stimulating acetyltransferase and transcriptional activity of the complex. Alternative splicing results in multiple transcript variants.
UniProt Protein Function:peregrin: Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Positively regulates the transcription of RUNX1 and RUNX2. 4 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: 3p26-p25

Cellular Component: nucleoplasm; cytoplasm; nucleus

Molecular Function:protein binding; DNA binding; zinc ion binding

Biological Process: establishment and/or maintenance of chromatin architecture; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent

NCBI Summary:The protein encoded by this gene is expressed ubiquitously and at the highest level in testes and spermatogonia. The protein is localized within nuclei, and it is very similar in structure to two zinc finger proteins, AF10 and AF17. It is suggested that these proteins form a family of regulatory proteins. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Code:P55201
NCBI GenInfo Identifier:51173719
NCBI Gene ID:7862
NCBI Accession:NP_001003694.1
UniProt Secondary Accession:P55201,Q7Z6E0, Q8TCM6, Q9UHI0, B4DEZ6,
UniProt Related Accession:P55201
Molecular Weight:127,363 Da
NCBI Full Name:Homo sapiens bromodomain and PHD finger containing, 1 (BRPF1), transcript variant 1, mRNA
NCBI Synonym Full Names:bromodomain and PHD finger containing, 1
NCBI Official Symbol:BRPF1  
NCBI Official Synonym Symbols:BR140  
NCBI Protein Information:peregrin; bromodomain and PHD finger-containing protein 1; bromodomain-containing protein, 140kD
UniProt Protein Name:Peregrin
UniProt Synonym Protein Names:Bromodomain and PHD finger-containing protein 1; Protein Br140
Protein Family:Peregrin
UniProt Gene Name:BRPF1  
UniProt Entry Name:BRPF1_HUMAN
View AllClose

0 Reviews

View AllClose

Related Products