Immunology Antibodies 3

Anti-BPIFA1 Antibody (CAB8634)

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SKU:
CAB8634
Product Type:
Antibody
Applications:
WB
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Immunology

Description

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Antibody Name:Anti-BPIFA1 Antibody
Antibody SKU:CAB8634
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 20-256 of human BPIFA1 (NP_057667.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse, Rat
Positive Samples:Mouse liver, Rat heart
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 20-256 of human BPIFA1 (NP_057667.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:QFGG LPVP LDQT LPLN VNPA LPLS PTGL AGSL TNAL SNGL LSGG LLGI LENL PLLD ILKP GGGT SGGL LGGL LGKV TSVI PGLN NIID IKVT DPQL LELG LVQS PDGH RLYV TIPL GIKL QVNT PLVG ASLL RLAV KLDI TAEI LAVR DKQE RIHL VLGD CTHS PGSL QISL LDGL GPLP IQGL LDSL TGIL NKVL PELV QGNV CPLV NEVL RGLD ITLV HDIV NMLI HGLQ FVIK V
Gene ID:51297
Uniprot:Q9NP55
Cellular Location:Secreted
Calculated MW:25kDa/26kDa
Observed MW:26kDa
Synonyms:BPIFA1, LUNX, NASG, PLUNC, SPLUNC1, SPURT, bA49G10.5
Background:This gene is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The encoded antimicrobial protein displays antibacterial activity against Gram-negative bacteria. It is thought to be involved in inflammatory responses to irritants in the upper airways and may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. Multiple transcript variants resulting from alternative splicing in the 3' UTR have been detected, but the full-length nature of only three are known.
NCBI Summary:This gene is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The encoded antimicrobial protein displays antibacterial activity against Gram-negative bacteria. It is thought to be involved in inflammatory responses to irritants in the upper airways and may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. Multiple transcript variants resulting from alternative splicing in the 3' UTR have been detected, but the full-length nature of only three are known. [provided by RefSeq, Aug 2014]
UniProt Code:Q9NP55
NCBI GenInfo Identifier:342307069
NCBI Gene ID:51297
NCBI Accession:NP_001230122.1
UniProt Related Accession:Q9NP55
Molecular Weight:
NCBI Full Name:BPI fold-containing family A member 1
NCBI Synonym Full Names:BPI fold containing family A member 1
NCBI Official Symbol:BPIFA1  
NCBI Official Synonym Symbols:LUNX; NASG; PLUNC; SPURT; SPLUNC1; bA49G10.5  
NCBI Protein Information:BPI fold-containing family A member 1
UniProt Protein Name:BPI fold-containing family A member 1
UniProt Synonym Protein Names:Lung-specific protein X; Nasopharyngeal carcinoma-related protein; Palate lung and nasal epithelium clone protein; Secretory protein in upper respiratory tracts; Short PLUNC1; SPLUNC1; Tracheal epithelium-enriched protein; Von Ebner protein Hl
UniProt Gene Name:BPIFA1  
UniProt Entry Name:BPIA1_HUMAN
Anti-BPIFA1 Polyclonal Antibody (CAB8634)Western blot analysis of extracts of various cell lines, using BPIFA1 antibody (CAB8634) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
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