Cell Biology Antibodies 11

Anti-BOC Antibody (CAB7174)

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SKU:
CAB7174
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-BOC Antibody
Antibody SKU:CAB7174
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-125 of human BOC (NP_150279.1).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:A-431, SW480, U-251MG, SKOV3, HeLa, Mouse lung, Mouse brain, Rat spinal cord
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-125 of human BOC (NP_150279.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MLRG TMTA WRGM RPEV TLAC LLLA TAGC FADL NEVP QVTV QPAS TVQK PGGT VILG CVVE PPRM NVTW RLNG KELN GSDD ALGV LITH GTLV ITAL NNHT VGRY QCVA RMPA GAVA SVPA TVTL A
Gene ID:91653
Uniprot:Q9BWV1
Cellular Location:Cell membrane, Single-pass type I membrane protein
Calculated MW:100kDa/121kDa
Observed MW:121kDa
Synonyms:BOC, CDON2
Background:The protein encoded by this gene is a member of the immunoglobulin/fibronectin type III repeat family. It is a component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells, and promotes myogenic differentiation. Alternative splicing results in multiple transcript variants encoding different isoforms.
UniProt Protein Function:BOC: Component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells. Promotes differentiation of myogenic cells. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Membrane protein, integral; Cell adhesion; Cell development/differentiation

Chromosomal Location of Human Ortholog: 3q13.2

Cellular Component: cell soma; plasma membrane; integral to membrane

Molecular Function:protein binding

Biological Process: axon guidance; smoothened signaling pathway; muscle cell differentiation; positive regulation of muscle cell differentiation; cell adhesion; positive regulation of myoblast differentiation

NCBI Summary:The protein encoded by this gene is a member of the immunoglobulin/fibronectin type III repeat family. It is a component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells, and promotes myogenic differentiation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2014]
UniProt Code:Q9BWV1
NCBI GenInfo Identifier:74761309
NCBI Gene ID:91653
NCBI Accession:Q9BWV1.1
UniProt Secondary Accession:Q9BWV1,Q6UXJ5, Q8N2P7, Q8NF26, A6NJ30, B2RMS8, D3DN70
UniProt Related Accession:Q9BWV1
Molecular Weight:1114
NCBI Full Name:Brother of CDO
NCBI Synonym Full Names:BOC cell adhesion associated, oncogene regulated
NCBI Official Symbol:BOC  
NCBI Official Synonym Symbols:CDON2  
NCBI Protein Information:brother of CDO; Boc homolog; brother of CDON; cell adhesion associated, oncogene regulated 2
UniProt Protein Name:Brother of CDO
Protein Family:Brother of CDO
UniProt Gene Name:BOC  
UniProt Entry Name:BOC_HUMAN
Anti-BOC Antibody (CAB7174)Western blot analysis of extracts of various cell lines, using BOC antibody (CAB7174) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s.
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