Anti-BNIP1 Antibody (CAB4405)
- SKU:
- CAB4405
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- NIP1
- Synonyms:
- SEC20
- Synonyms:
- TRG-8
- Research Area:
- Cell Death
Description
| Product Name: | BNIP1 Rabbit mAb |
| Product Code: | CAB4405 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | NIP1, SEC20, TRG-8 |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human BNIP1 |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse heart, Rat heart |
| Immunogen: | A synthesized peptide derived from human BNIP1 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 662 |
| Uniprot: | Q12981 |
| Calculated MW: | 26kDa |
| Observed MW: | 26KDa |
| UniProt Protein Function: | BNIP1: SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER. Required for maintenance of ER network. Implicated in the suppression of cell death. May be involved in mitochondrial autophagy. Belongs to the SEC20 family. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Apoptosis Chromosomal Location of Human Ortholog: 5q33-q34 Cellular Component: SNARE complex; mitochondrion; intracellular membrane-bound organelle; endoplasmic reticulum; cytoplasm; integral to endoplasmic reticulum membrane; nuclear envelope Molecular Function:SNAP receptor activity; protein binding Biological Process: endoplasmic reticulum organization and biogenesis; endoplasmic reticulum membrane fusion; vesicle-mediated transport; apoptosis; autophagy; negative regulation of apoptosis |
| NCBI Summary: | This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. In addition, this protein is involved in vesicle transport into the endoplasmic reticulum. Alternative splicing of this gene results in four protein products with identical N- and C-termini. [provided by RefSeq, Mar 2011] |
| UniProt Code: | Q12981 |
| NCBI GenInfo Identifier: | 93141310 |
| NCBI Gene ID: | 662 |
| NCBI Accession: | Q12981.3 |
| UniProt Secondary Accession: | Q12981,O75622, O75623, O75624, Q6K044, Q96FG4, D3DQM3 D3DQM4, D3DQM5, D3DQM6, |
| UniProt Related Accession: | Q12981 |
| Molecular Weight: | 228 |
| NCBI Full Name: | Vesicle transport protein SEC20 |
| NCBI Synonym Full Names: | BCL2/adenovirus E1B 19kDa interacting protein 1 |
| NCBI Official Symbol: | BNIP1 |
| NCBI Official Synonym Symbols: | NIP1; SEC20; TRG-8 |
| NCBI Protein Information: | vesicle transport protein SEC20; transformation-related gene 8 protein; BCL2/adenovirus E1B 19 kDa protein-interacting protein 1 |
| UniProt Protein Name: | Vesicle transport protein SEC20 |
| UniProt Synonym Protein Names: | BCL2/adenovirus E1B 19 kDa protein-interacting protein 1; Transformation-related gene 8 protein; TRG-8 |
| Protein Family: | Vesicle transport protein |
| UniProt Gene Name: | BNIP1 |
| UniProt Entry Name: | SEC20_HUMAN |
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