Anti-BMP4 Antibody (CAB21065)
- SKU:
- CAB21065
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Host Species:
- Rabbit
- Reactivity:
- Universal
- Isotype:
- IgG1
Description
| Antibody Name: | Anti-BMP4 Antibody (CAB21065) |
| Antibody SKU: | CAB21065 |
| Antibody Size: | 50µL, 100µL |
| Application: | Western blotting |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 250-350 of human BMP4 (NP_001193.2). |
| Application: | Western blotting |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | A-549, U-937, Mouse lung, Rat lung |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 250-350 of human BMP4 (NP_001193.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | QHVR ISRS LPQG SGNW AQLR PLLV TFGH DGRG HALT RRRR AKRS PKHH SQRA RKKN KNCR RHSL YVDF SDVG WNDW IVAP PGYQ AFYC HGDC PFPL ADHL N |
| Cellular Location: | Secreted, extracellular matrix, extracellular space |
| Calculated MW: | 47kDa |
| Observed MW: | 47kDa |
| Synonyms: | BMP2B, BMP2B1, MCOPS6, OFC11, ZYME |
| Background: | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers. provided by RefSeq, Jul 2016 |
 | Western blot analysis of extracts of Rat lung, using BMP4 antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s. |
 | Western blot analysis of extracts of various cell lines, using BMP4 antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s. |
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