Cell Biology Antibodies 7
Anti-BMP1 Antibody (CAB16353)
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- SKU:
- CAB16353
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-BMP1 Antibody |
| Antibody SKU: | CAB16353 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | IF |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 725-986 of human BMP1 (NP_006120.1). |
| Application: | IF |
| Recommended Dilution: | IF 1:50 - 1:200 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 725-986 of human BMP1 (NP_006120.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | YECQ CRSG FVLH DNKH DCKE AGCD HKVT STSG TITS PNWP DKYP SKKE CTWA ISST PGHR VKLT FMEM DIES QPEC AYDH LEVF DGRD AKAP VLGR FCGS KKPE PVLA TGSR MFLR FYSD NSVQ RKGF QASH ATEC GGQV RADV KTKD LYSH AQFG DNNY PGGV DCEW VIVA EEGY GVEL VFQT FEVE EETD CGYD YMEL FDGY DSTA PRLG RYCG SGPP EEVY SAGD SVLV KFHS DDTI TKKG FHLR YTST KFQD TLHS RK |
| Gene ID: | 649 |
| Uniprot: | P13497 |
| Cellular Location: | Golgi apparatus, Secreted, extracellular matrix, extracellular space, trans-Golgi network |
| Calculated MW: | 33kDa/70kDa/81kDa/82kDa/92kDa/111kDa |
| Observed MW: |
| Synonyms: | BMP1, OI13, PCOLC, PCP, PCP2, TLD |
| Background: | This gene encodes a protein that is capable of inducing formation of cartilage in vivo. Although other bone morphogenetic proteins are members of the TGF-beta superfamily, this gene encodes a protein that is not closely related to other known growth factors. This gene is expressed as alternatively spliced variants that share an N-terminal protease domain but differ in their C-terminal region. |
| UniProt Protein Function: | Cleaves the C-terminal propeptides of procollagen I, II and III. Induces cartilage and bone formation. May participate in dorsoventral patterning during early development by cleaving chordin (CHRD). Responsible for the proteolytic activation of lysyl oxidase LOX. |
| NCBI Summary: | This gene encodes a protein that is capable of inducing formation of cartilage in vivo. Although other bone morphogenetic proteins are members of the TGF-beta superfamily, this gene encodes a protein that is not closely related to other known growth factors. This gene is expressed as alternatively spliced variants that share an N-terminal protease domain but differ in their C-terminal region. [provided by RefSeq, Aug 2008] |
| UniProt Code: | P13497 |
| NCBI GenInfo Identifier: | 13124688 |
| NCBI Gene ID: | 649 |
| NCBI Accession: | P13497.2 |
| UniProt Secondary Accession: | P13497,Q13292, Q13872, Q14874, Q99421, Q99422, Q99423 Q9UL38, A8K6F5, B2RN46, D3DSR0, |
| UniProt Related Accession: | P13497 |
| Molecular Weight: | 82,900 Da |
| NCBI Full Name: | Bone morphogenetic protein 1 |
| NCBI Synonym Full Names: | bone morphogenetic protein 1 |
| NCBI Official Symbol: | BMP1 |
| NCBI Official Synonym Symbols: | PCP; TLD; OI13; PCP2; PCOLC |
| NCBI Protein Information: | bone morphogenetic protein 1 |
| UniProt Protein Name: | Bone morphogenetic protein 1 |
| UniProt Synonym Protein Names: | Mammalian tolloid protein; mTld; Procollagen C-proteinase; PCP |
| Protein Family: | Bone morphogenetic protein |
| UniProt Gene Name: | BMP1 |
 | Immunofluorescence analysis of HeLa cells using BMP1 antibody (CAB16353) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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