Cell Biology Antibodies 9
Anti-BLVRA Antibody (CAB3765)
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- SKU:
- CAB3765
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-BLVRA Antibody |
| Antibody SKU: | CAB3765 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-296 of human BLVRA (NP_001240752.1). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:100 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse kidney |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-296 of human BLVRA (NP_001240752.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MNAE PERK FGVV VVGV GRAG SVRM RDLR NPHP SSAF LNLI GFVS RREL GSID GVQQ ISLE DALS SQEV EVAY ICSE SSSH EDYI RQFL NAGK HVLV EYPM TLSL AAAQ ELWE LAEQ KGKV LHEE HVEL LMEE FAFL KKEV VGKD LLKG SLLF TAGP LEEE RFGF PAFS GISR LTWL VSLF GELS LVSA TLEE RKED QYMK MTVC LETE KKSP LSWI EEKG PGLK RNRY LSFH FKSG SLEN VPNV GVNK NIFL KDQN IFVQ KLLG QFSE KELA AEKK RILH CLGL AEEI QKYC CSRK |
| Gene ID: | 644 |
| Uniprot: | P53004 |
| Cellular Location: | Cytoplasm |
| Calculated MW: | 33kDa |
| Observed MW: | 33kDa |
| Synonyms: | BLVRA, BLVR, BVR, BVRA |
| Background: | The protein encoded by this gene belongs to the biliverdin reductase family, members of which catalyze the conversion of biliverdin to bilirubin in the presence of NADPH or NADH. Mutations in this gene are associated with hyperbiliverdinemia. Alternatively spliced transcript variants have been found for this gene. |
| UniProt Protein Function: | BVR: Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor. Monomer. Liver. Belongs to the Gfo/Idh/MocA family. Biliverdin reductase subfamily. |
| UniProt Protein Details: | Protein type:Oxidoreductase; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Cofactor and Vitamin Metabolism - porphyrin and chlorophyll; EC 1.3.1.24; ATYPICAL group; BLVRA family Chromosomal Location of Human Ortholog: 7p13 Cellular Component: cytosol Molecular Function:zinc ion binding; biliverdin reductase activity Biological Process: heme catabolic process; porphyrin metabolic process Disease: Hyperbiliverdinemia |
| NCBI Summary: | The protein encoded by this gene belongs to the biliverdin reductase family, members of which catalyze the conversion of biliverdin to bilirubin in the presence of NADPH or NADH. Mutations in this gene are associated with hyperbiliverdinemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2011] |
| UniProt Code: | P53004 |
| NCBI GenInfo Identifier: | 23830892 |
| NCBI Gene ID: | 644 |
| NCBI Accession: | P53004.2 |
| UniProt Related Accession: | P53004 |
| Molecular Weight: | |
| NCBI Full Name: | Biliverdin reductase A |
| NCBI Synonym Full Names: | biliverdin reductase A |
| NCBI Official Symbol: | BLVRA |
| NCBI Official Synonym Symbols: | BVR; BLVR; BVRA |
| NCBI Protein Information: | biliverdin reductase A |
| UniProt Protein Name: | Biliverdin reductase A |
| UniProt Synonym Protein Names: | Biliverdin-IX alpha-reductase |
| UniProt Gene Name: | BLVRA |
| UniProt Entry Name: | BIEA_HUMAN |
 | Western blot analysis of extracts of mouse kidney, using BLVRA antibody (CAB3765) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 90s. |
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