Cell Death Antibodies 2

Anti-BIRC8 Antibody (CAB7143)

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SKU:
CAB7143
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Death

Description

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Antibody Name:Anti-BIRC8 Antibody
Antibody SKU:CAB7143
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-236 of human BIRC8 (NP_203127.3).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:HepG2, SKOV3, Mouse spleen, Mouse testis, Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-236 of human BIRC8 (NP_203127.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MTGY EARL ITFG TWMY SVNK EQLA RAGF YAIG QEDK VQCF HCGG GLAN WKPK EDPW EQHA KWYP GCKY LLEE KGHE YINN IHLT RSLE GALV QTTK KTPS LTKR ISDT IFPN PMLQ EAIR MGFD FKDV KKIM EERI QTSG SNYK TLEV LVAD LVSA QKDT TENE LNQT SLQR EISP EEPL RRLQ EEKL CKIC MDRH IAVV FIPC GHLV TCKQ CAEA VDRC PMCS AVID FKQR VFMS
Gene ID:112401
Uniprot:Q96P09
Cellular Location:Cytoplasm
Calculated MW:27kDa
Observed MW:27kDa
Synonyms:BIRC8, ILP-2, ILP2, hILP2
Background:
UniProt Protein Function:BIRC8: Protects against apoptosis mediated by BAX. Belongs to the IAP family.
UniProt Protein Details:

Protein type:Ubiquitin conjugating system; Apoptosis

Chromosomal Location of Human Ortholog: -

Cellular Component: spindle microtubule; perinuclear region of cytoplasm; cytoplasm; nucleus; cytosol

Molecular Function:protease binding; zinc ion binding; caspase inhibitor activity; ubiquitin-protein ligase activity

Biological Process: neuron apoptosis; protein ubiquitination; negative regulation of neuron apoptosis; negative regulation of apoptosis

UniProt Code:Q96P09
NCBI GenInfo Identifier:311033354
NCBI Gene ID:112401
NCBI Accession:Q96P09.2
UniProt Secondary Accession:Q96P09,Q6IPY1, Q96RW5,
UniProt Related Accession:Q96P09
Molecular Weight:236
NCBI Full Name:Baculoviral IAP repeat-containing protein 8
NCBI Synonym Full Names:baculoviral IAP repeat containing 8
NCBI Official Symbol:BIRC8  
NCBI Official Synonym Symbols:ILP2; ILP-2; hILP2  
NCBI Protein Information:baculoviral IAP repeat-containing protein 8; IAP-like protein 2; baculoviral IAP repeat-containing 8; inhibitor of apoptosis-like protein 2; testis-specific inhibitor of apoptosis
UniProt Protein Name:Baculoviral IAP repeat-containing protein 8
UniProt Synonym Protein Names:Inhibitor of apoptosis-like protein 2; IAP-like protein 2; ILP-2; Testis-specific inhibitor of apoptosis
Protein Family:Baculoviral IAP repeat-containing protein
UniProt Gene Name:BIRC8  
UniProt Entry Name:BIRC8_HUMAN
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