Cell Biology Antibodies 18
Anti-BICD1 Antibody (CAB18340)
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- SKU:
- CAB18340
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-BICD1 Antibody |
| Antibody SKU: | CAB18340 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human BICD1. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant protein of human BICD1. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 636 |
| Uniprot: | Q96G01 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
| Synonyms: | BICD, BICD1 |
| Background: |
| UniProt Protein Function: | BICD1: Regulates coat complex coatomer protein I (COPI)- independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex. Belongs to the BicD family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Vesicle Chromosomal Location of Human Ortholog: 12p11.2-p11.1 Cellular Component: Golgi apparatus; cytoskeleton; membrane; cytoplasmic microtubule; perinuclear region of cytoplasm; tubulin complex; cytoplasmic vesicle; trans-Golgi network; cytosol Molecular Function:dynein binding; protein binding; proteinase activated receptor binding; structural constituent of cytoskeleton; cytoskeletal adaptor activity; Rab GTPase binding Biological Process: RNA processing; stress granule assembly; intracellular mRNA localization; anatomical structure morphogenesis; viral reproduction; protein localization in organelle; positive regulation of receptor-mediated endocytosis |
| NCBI Summary: | This gene encodes an adaptor protein that belongs to the bicaudal D family of dynein cargo adaptors. The encoded protein acts as an intracellular cargo transport cofactor that regulates the microtubule-based loading of cargo onto the dynein motor complex. It also controls dynein motor activity and coordination. It has a domain architecture consisting of coiled-coil domains at the N- and C-termini that are highly conserved in other family members. Naturally occurring mutations in this gene are associated with short telomere length and emphysema. [provided by RefSeq, Aug 2017] |
| UniProt Code: | Q96G01 |
| NCBI GenInfo Identifier: | 51039802 |
| NCBI Gene ID: | 636 |
| NCBI Accession: | NP_001705 |
| UniProt Related Accession: | Q96G01 |
| Molecular Weight: | 91kDa |
| NCBI Full Name: | protein bicaudal D homolog 1 isoform 1 |
| NCBI Synonym Full Names: | BICD cargo adaptor 1 |
| NCBI Official Symbol: | BICD1 |
| NCBI Official Synonym Symbols: | BICD; bic-D 1 |
| NCBI Protein Information: | protein bicaudal D homolog 1 |
| UniProt Protein Name: | Protein bicaudal D homolog 1 |
| Protein Family: | Protein bicaudal |
| UniProt Gene Name: | BICD1 |
| UniProt Entry Name: | BICD1_HUMAN |
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