Cell Biology Antibodies 17
Anti-BHMT Antibody (CAB5134)
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- SKU:
- CAB5134
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-BHMT Antibody |
| Antibody SKU: | CAB5134 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human BHMT |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HepG2, Mouse liver, Mouse kidney, Rat liver |
| Immunogen: | A synthesized peptide derived from human BHMT |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 635 |
| Uniprot: | Q93088 |
| Cellular Location: | |
| Calculated MW: | 45kDa |
| Observed MW: | 45KDa |
| Synonyms: | BHMT1, HEL-S-61p |
| Background: | This gene encodes a cytosolic enzyme that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. Defects in this gene could lead to hyperhomocyst(e)inemia, but such a defect has not yet been observed. [provided by RefSeq, Jul 2008] |
| UniProt Protein Function: | BHMT: Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline. |
| UniProt Protein Details: | Protein type:Amino Acid Metabolism - glycine, serine and threonine; Amino Acid Metabolism - cysteine and methionine; EC 2.1.1.5; Methyltransferase Chromosomal Location of Human Ortholog: 5q14.1 Cellular Component: protein complex; cytoplasm; cytosol Molecular Function:betaine-homocysteine S-methyltransferase activity; homocysteine S-methyltransferase activity; zinc ion binding; protein complex binding Biological Process: S-methylmethionine cycle; protein amino acid methylation; betaine catabolic process; sulfur amino acid metabolic process; S-adenosylmethionine metabolic process; response to organic nitrogen; regulation of homocysteine metabolic process; betaine metabolic process |
| NCBI Summary: | This gene encodes a cytosolic enzyme that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. Defects in this gene could lead to hyperhomocyst(e)inemia, but such a defect has not yet been observed. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q93088 |
| NCBI GenInfo Identifier: | 145559446 |
| NCBI Gene ID: | 635 |
| NCBI Accession: | Q93088.2 |
| UniProt Secondary Accession: | Q93088,O09171, |
| UniProt Related Accession: | Q93088 |
| Molecular Weight: | 45kDa |
| NCBI Full Name: | Betaine--homocysteine S-methyltransferase 1 |
| NCBI Synonym Full Names: | betaine--homocysteine S-methyltransferase |
| NCBI Official Symbol: | BHMT |
| NCBI Official Synonym Symbols: | BHMT1; HEL-S-61p |
| NCBI Protein Information: | betaine--homocysteine S-methyltransferase 1 |
| UniProt Protein Name: | Betaine--homocysteine S-methyltransferase 1 |
| Protein Family: | Betaine--homocysteine S-methyltransferase |
| UniProt Gene Name: | BHMT |
| UniProt Entry Name: | BHMT1_HUMAN |
 | Western blot - BHMT Rabbit mAb (CAB5134) |
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