Cell Biology Antibodies 17

Anti-BHMT Antibody (CAB5134)

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SKU:
CAB5134
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-BHMT Antibody
Antibody SKU:CAB5134
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human BHMT
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:HepG2, Mouse liver, Mouse kidney, Rat liver
Immunogen:A synthesized peptide derived from human BHMT
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:635
Uniprot:Q93088
Cellular Location:
Calculated MW:45kDa
Observed MW:45KDa
Synonyms:BHMT1, HEL-S-61p
Background:This gene encodes a cytosolic enzyme that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. Defects in this gene could lead to hyperhomocyst(e)inemia, but such a defect has not yet been observed. [provided by RefSeq, Jul 2008]
UniProt Protein Function:BHMT: Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline.
UniProt Protein Details:

Protein type:Amino Acid Metabolism - glycine, serine and threonine; Amino Acid Metabolism - cysteine and methionine; EC 2.1.1.5; Methyltransferase

Chromosomal Location of Human Ortholog: 5q14.1

Cellular Component: protein complex; cytoplasm; cytosol

Molecular Function:betaine-homocysteine S-methyltransferase activity; homocysteine S-methyltransferase activity; zinc ion binding; protein complex binding

Biological Process: S-methylmethionine cycle; protein amino acid methylation; betaine catabolic process; sulfur amino acid metabolic process; S-adenosylmethionine metabolic process; response to organic nitrogen; regulation of homocysteine metabolic process; betaine metabolic process

NCBI Summary:This gene encodes a cytosolic enzyme that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. Defects in this gene could lead to hyperhomocyst(e)inemia, but such a defect has not yet been observed. [provided by RefSeq, Jul 2008]
UniProt Code:Q93088
NCBI GenInfo Identifier:145559446
NCBI Gene ID:635
NCBI Accession:Q93088.2
UniProt Secondary Accession:Q93088,O09171,
UniProt Related Accession:Q93088
Molecular Weight:45kDa
NCBI Full Name:Betaine--homocysteine S-methyltransferase 1
NCBI Synonym Full Names:betaine--homocysteine S-methyltransferase
NCBI Official Symbol:BHMT  
NCBI Official Synonym Symbols:BHMT1; HEL-S-61p  
NCBI Protein Information:betaine--homocysteine S-methyltransferase 1
UniProt Protein Name:Betaine--homocysteine S-methyltransferase 1
Protein Family:Betaine--homocysteine S-methyltransferase
UniProt Gene Name:BHMT  
UniProt Entry Name:BHMT1_HUMAN
Anti-BHMT Antibody (CAB5134)Western blot - BHMT Rabbit mAb (CAB5134)
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