Cell Biology Antibodies 17

Anti-BGAT Antibody (CAB5207)

(No reviews yet) Write a Review
SKU:
CAB5207
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-BGAT Antibody
Antibody SKU:CAB5207
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human BGAT
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:HT-29, THP-1
Immunogen:A synthesized peptide derived from human BGAT
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:28
Uniprot:P16442
Cellular Location:
Calculated MW:41kDa
Observed MW:41KDa
Synonyms:A3GALNT, A3GALT1, GTB, NAGAT
Background:This gene encodes proteins related to the first discovered blood group system, ABO. Which allele is present in an individual determines the blood group. The 'O' blood group is caused by a deletion of guanine-258 near the N-terminus of the protein which results in a frameshift and translation of an almost entirely different protein. Individuals with the A, B, and AB alleles express glycosyltransferase activities that convert the H antigen into the A or B antigen. Other minor alleles have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Protein Function:ABO: This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. Belongs to the glycosyltransferase 6 family.
UniProt Protein Details:

Protein type:Glycan Metabolism - glycosphingolipid biosynthesis - lacto and neolacto series; EC 2.4.1.37; Membrane protein, integral; EC 2.4.1.40; Transferase

Chromosomal Location of Human Ortholog: 9q34.2

Cellular Component: integral to membrane; extracellular region

Molecular Function:metal ion binding; glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity; fucosylgalactoside 3-alpha-galactosyltransferase activity

Biological Process: protein amino acid glycosylation

Disease: Blood Group, Abo System

NCBI Summary:This gene encodes proteins related to the first discovered blood group system, ABO. Which allele is present in an individual determines the blood group. The 'O' blood group is caused by a deletion of guanine-258 near the N-terminus of the protein which results in a frameshift and translation of an almost entirely different protein. Individuals with the A, B, and AB alleles express glycosyltransferase activities that convert the H antigen into the A or B antigen. Other minor alleles have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Code:P16442
NCBI GenInfo Identifier:114949
NCBI Gene ID:28
NCBI Accession:P16442.2
UniProt Related Accession:P16442
Molecular Weight:
NCBI Full Name:Histo-blood group ABO system transferase
NCBI Synonym Full Names:ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase
NCBI Official Symbol:ABO  
NCBI Official Synonym Symbols:GTB; NAGAT; A3GALNT; A3GALT1  
NCBI Protein Information:histo-blood group ABO system transferase
UniProt Protein Name:Histo-blood group ABO system transferase
UniProt Synonym Protein Names:Fucosylglycoprotein 3-alpha-galactosyltransferase; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase; Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase (EC:2.4.1.40); Glycoprotein-fucosylgalactoside alpha-galactosyltransferase (EC:2.4.1.37); Histo-blood group A transferase; A transferase; Histo-blood group B transferase; B transferase; NAGATFucosylglycoprotein alpha-N-acetylgalactosaminyltransferase soluble form
Protein Family:4-methylaminobutanoate oxidase
UniProt Gene Name:ABO  
UniProt Entry Name:BGAT_HUMAN
Anti-BGAT Antibody (CAB5207)Western blot - BGAT Rabbit mAb (CAB5207)
View AllClose

0 Reviews

View AllClose

Related Products