Cell Biology Antibodies 14
Anti-BES1 Antibody (CAB16262)
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- SKU:
- CAB16262
- Product Type:
- Antibody
- Reactivity:
- Plant - Arabidopsis
- Reactivity:
- Plant
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-BES1 Antibody |
| Antibody SKU: | CAB16262 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Arabidopsis thaliana, Rice |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human BES1 |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Arabidopsis thaliana, Rice |
| Positive Samples: |
| Immunogen: | Recombinant protein of human BES1 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 838518 |
| Uniprot: | Q9LN63 |
| Cellular Location: | |
| Calculated MW: | 36kDa |
| Observed MW: | Refer to figures |
| Synonyms: | BES1, BZR2, 107 PROTEIN, BRASSINAZOLE-RESISTANT 2, BRI1-EMS-SUPPRESSOR 1, F18O14.7, F18O14_7 |
| Background: | Encodes brassinosteroid (BR) signalling protein that accumulates in the nucleus as dephosphorylated form in response to BRs. Is phosphorylated by the BIN2 GSK3 kinase. It synergistically interacts with BIM1 to bind to E box sequences (CANNTG). The protein contains a nuclear localization signal (NLS), followed by a highly conserved amino-terminal domain (N) shared by all family members, a BIN2 phosphorylation domain (P), a PEST motif, involved in protein degradation in the absence of BR, and a carboxyl-terminal domain. BES1 can interact with the ELF6 and REF6 Jumonji N/C-domain containing proteins and may direct them to modify histone methylation upstream of some brassinosteroid responsive-genes. Works with BRAVO to regulate QC division in the root. |
| UniProt Protein Function: | Positive regulator of brassinosteroid (BR) signaling. Transcription factor that activates target gene expression by binding specifically to the DNA sequence 5'-CANNTG-3'(E box) through its N-terminal domain. Can bind individually to the promoter as a homodimer or synergistically as a heterodimer with BIM1, BIM2 or BIM3. The C-terminal domain is probably involved in transcriptional activation (PubMed:12007405, PubMed:15680330, PubMed:18467490, PubMed:19170933). Recruits the transcription elongation factor IWS1 to control BR-regulated gene expression (PubMed:20139304). Forms a trimeric complex with IWS1 and ASHH2/SDG8 to regulate BR-regulated gene expression (PubMed:24838002). Promotes quiescent center (QC) self-renewal by cell divisions in the primary root. Binds to the E-boxes of the BRAVO promoter to repress its expression (PubMed:24981610). |
| NCBI Summary: | Encodes brassinosteroid (BR) signalling protein that accumulates in the nucleus as dephosphorylated form in response to BRs. Is phosphorylated by the BIN2 GSK3 kinase. It synergistically interacts with BIM1 to bind to E box sequences (CANNTG). The protein contains a nuclear localization signal (NLS), followed by a highly conserved amino-terminal domain (N) shared by all family members, a BIN2 phosphorylation domain (P), a PEST motif, involved in protein degradation in the absence of BR, and a carboxyl-terminal domain. BES1 can interact with the ELF6 and REF6 Jumonji N/C-domain containing proteins and may direct them to modify histone methylation upstream of some brassinosteroid responsive-genes. Works with BRAVO to regulate QC division in the root. |
| UniProt Code: | Q9LN63 |
| NCBI GenInfo Identifier: | 57012618 |
| NCBI Gene ID: | 838518 |
| NCBI Accession: | Q9LN63.1 |
| UniProt Secondary Accession: | Q9LN63,Q8LCX8, Q94JU1, Q9SEG5, |
| UniProt Related Accession: | Q9LN63 |
| Molecular Weight: | 335 aa |
| NCBI Full Name: | Protein BRASSINAZOLE-RESISTANT 2 |
| NCBI Official Symbol: | BES1 |
| NCBI Official Synonym Symbols: | 107 PROTEIN; BRASSINAZOLE-RESISTANT 2; BRI1-EMS-SUPPRESSOR 1; BZR2; F18O14.7; F18O14_7 |
| NCBI Protein Information: | Brassinosteroid signaling positive regulator (BZR1) family protein |
| UniProt Protein Name: | Protein BRASSINAZOLE-RESISTANT 2 |
| UniProt Synonym Protein Names: | Protein 107; Protein BIN2 SUBSTRATE 1 |
| Protein Family: | Protein |
| UniProt Gene Name: | BZR2 |
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