Cell Death Antibodies 2
Anti-BCL2L14 Antibody (CAB6478)
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- SKU:
- CAB6478
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Description
| Antibody Name: | Anti-BCL2L14 Antibody |
| Antibody SKU: | CAB6478 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-327 of human BCL2L14 (NP_620049.1). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:10 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse liver, Rat liver, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-327 of human BCL2L14 (NP_620049.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MCST SGCD LEEI PLDD DDLN TIEF KILA YYTR HHVF KSTP ALFS PKLL RTRS LSQR GLGN CSAN ESWT EVSW PCRN SQSS EKAI NLGK KKSS WKAF FGVV EKED SQST PAKV SAQG QRTL EYQD SHSQ QWSR CLSN VEQC LEHE AVDP KVIS IANR VAEI VYSW PPPQ ATQA GGFK SKEI FVTE GLSF QLQG HVPV ASSS KKDE EEQI LAKI VELL KYSG DQLE RKLK KDKA LMGH FQDG LSYS VFKT ITDQ VLMG VDPR GESE VKAQ GFKA ALVI DVTA KLTA IDNH PMNR VLGF GTKY LKEN FSPW IQQH GGWE KILG ISHE EVD |
| Gene ID: | 79370 |
| Uniprot: | Q9BZR8 |
| Cellular Location: | Cytoplasm, Endomembrane system, cytosol |
| Calculated MW: | 28kDa/30kDa/36kDa |
| Observed MW: | 39kDa |
| Synonyms: | BCL2L14, BCLG |
| Background: | The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Overexpression of this gene has been shown to induce apoptosis in cells. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported for this gene. |
| UniProt Protein Function: | Bcl-G: Plays a role in apoptosis. Belongs to the Bcl-2 family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Apoptosis Chromosomal Location of Human Ortholog: 12p13-p12 Cellular Component: cytoplasm; cytosol; intracellular organelle Molecular Function:protein binding; protein kinase binding Biological Process: apoptosis; regulation of apoptosis |
| NCBI Summary: | The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Overexpression of this gene has been shown to induce apoptosis in cells. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported for this gene. [provided by RefSeq, May 2009] |
| UniProt Code: | Q9BZR8 |
| NCBI GenInfo Identifier: | 56748611 |
| NCBI Gene ID: | 79370 |
| NCBI Accession: | Q9BZR8.1 |
| UniProt Secondary Accession: | Q9BZR8,Q96QR5, Q9BZR7, A8KAD0, |
| UniProt Related Accession: | Q9BZR8 |
| Molecular Weight: | 30,948 Da |
| NCBI Full Name: | Apoptosis facilitator Bcl-2-like protein 14 |
| NCBI Synonym Full Names: | BCL2 like 14 |
| NCBI Official Symbol: | BCL2L14 |
| NCBI Official Synonym Symbols: | BCLG |
| NCBI Protein Information: | apoptosis facilitator Bcl-2-like protein 14 |
| UniProt Protein Name: | Apoptosis facilitator Bcl-2-like protein 14 |
| UniProt Synonym Protein Names: | Apoptosis regulator Bcl-G |
| Protein Family: | Apoptosis facilitator Bcl-2-like protein |
| UniProt Gene Name: | BCL2L14 |
| UniProt Entry Name: | B2L14_HUMAN |
 | Western blot analysis of extracts of various cell lines, using BCL2L14 antibody (CAB6478) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunofluorescence analysis of HeLa cells using BCL2L14 antibody (CAB6478). Blue: DAPI for nuclear staining. |
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