Epigenetics & Nuclear Signaling Antibodies 4
Anti-BAZ1A Antibody (CAB9866)
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- SKU:
- CAB9866
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-BAZ1A Antibody |
| Antibody SKU: | CAB9866 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1347-1556 of human BAZ1A (NP_038476.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, Mouse lung, Mouse spleen, Rat lung, Rat skeletal muscle |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1347-1556 of human BAZ1A (NP_038476.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | VFVE LLSP RRKR RGRK SANN TPEN SPNF PNFR VIAT KSSE QSRS VNIA SKLS LQES ESKR RCRK RQSP EPSP VTLG RRSS GRQG GVHE LSAF EQLV VELV RHDD SWPF LKLV SKIQ VPDY YDII KKPI ALNI IREK VNKC EYKL ASEF IDDI ELMF SNCF EYNP RNTS EAKA GTRL QAFF HIQA QKLG LHVT PSNV DQVS TPPA AKKS RI |
| Gene ID: | 11177 |
| Uniprot: | Q9NRL2 |
| Cellular Location: | Nucleus |
| Calculated MW: | 175kDa/178kDa |
| Observed MW: | 250kDa |
| Synonyms: | BAZ1A, ACF1, WALp1, WCRF180, hACF1 |
| Background: |
| UniProt Protein Function: | ACP2: Defects in ACP2 are a cause of acid phosphatase deficiency (ACPHD). The clinical features are intermittent vomiting, hypotonia, lethargy, opisthotonos, terminal bleeding, and death in early infancy. Lysosomal acid phosphatase is deficient in cultured fibroblasts and multiple tissues. Belongs to the histidine acid phosphatase family. |
| UniProt Protein Details: | Protein type:Cofactor and Vitamin Metabolism - riboflavin; EC 3.1.3.2; Membrane protein, integral; Motility/polarity/chemotaxis; Phosphatase (non-protein) Chromosomal Location of Human Ortholog: 11p11.2|11p12-p11 Cellular Component: lysosome; membrane Disease: Acid Phosphatase Deficiency |
| NCBI Summary: | The BAZ1A gene encodes the accessory subunit of the ATP-dependent chromatin assembly factor (ACF), a member of the ISWI ('imitation switch') family of chromatin remodeling complexes (summarized by Racki et al., 2009 [PubMed 20033039]).[supplied by OMIM, Apr 2010] |
| UniProt Code: | Q9NRL2 |
| NCBI GenInfo Identifier: | 32967603 |
| NCBI Gene ID: | 11177 |
| NCBI Accession: | NP_038476 |
| UniProt Related Accession: | Q9NRL2 |
| Molecular Weight: | 179kDa |
| NCBI Full Name: | bromodomain adjacent to zinc finger domain protein 1A isoform a |
| NCBI Synonym Full Names: | bromodomain adjacent to zinc finger domain 1A |
| NCBI Official Symbol: | BAZ1A |
| NCBI Official Synonym Symbols: | ACF1; WALp1; hACF1; WCRF180 |
| NCBI Protein Information: | bromodomain adjacent to zinc finger domain protein 1A |
| UniProt Protein Name: | Lysosomal acid phosphatase |
| Protein Family: | Cysteine proteinase |
| UniProt Gene Name: | ACP2 |
| UniProt Entry Name: | PPAL_HUMAN |
 | Western blot analysis of extracts of various cell lines, using BAZ1A antibody (CAB9866) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
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