Epigenetics & Nuclear Signaling Antibodies 2

Anti-BATF3 Antibody (CAB14906)

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SKU:
CAB14906
Product Type:
Antibody
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling

Description

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Antibody Name:Anti-BATF3 Antibody
Antibody SKU:CAB14906
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-127 of human BATF3 (NP_061134.1).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:100
Reactivity:Rat
Positive Samples:Rat spleen
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-127 of human BATF3 (NP_061134.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MSQG LPAA GSVL QRSV AAPG NQPQ PQPQ QQSP EDDD RKVR RREK NRVA AQRS RKKQ TQKA DKLH EEYE SLEQ ENTM LRRE IGKL TEEL KHLT EALK EHEK MCPL LLCP MNFV PVPP RPDP VAGC LPR
Gene ID:55509
Uniprot:Q9NR55
Cellular Location:Nucleus
Calculated MW:14kDa
Observed MW:14kDa
Synonyms:BATF3, JDP1, JUNDM1, SNFT
Background:This gene encodes a member of the basic leucine zipper protein family. The encoded protein functions as a transcriptional repressor when heterodimerizing with JUN. The protein may play a role in repression of interleukin-2 and matrix metalloproteinase-1 transcription.
UniProt Protein Function:BATF3: Functions as a negative regulator of AP-1-mediated transcription by heterodimerizing with JUN and binding DNA at 12- O-tetradecanoylphorbol-13-acetate response elements (TRE) (consensus: 5'-TGA[CG]TCA-3'). Represses IL2 and MMP1 promoter activities. Belongs to the bZIP family.
UniProt Protein Details:

Protein type:DNA-binding

Chromosomal Location of Human Ortholog: 1q32.3

Cellular Component: nucleus

Molecular Function:protein binding; transcription corepressor activity; transcription factor activity

Biological Process: myeloid dendritic cell differentiation; negative regulation of transcription from RNA polymerase II promoter; response to virus; transcription from RNA polymerase II promoter

NCBI Summary:This gene encodes a member of the basic leucine zipper protein family. The encoded protein functions as a transcriptional repressor when heterodimerizing with JUN. The protein may play a role in repression of interleukin-2 and matrix metalloproteinase-1 transcription.[provided by RefSeq, Feb 2009]
UniProt Code:Q9NR55
NCBI GenInfo Identifier:74752916
NCBI Gene ID:55509
NCBI Accession:Q9NR55.1
UniProt Secondary Accession:Q9NR55,Q9D275, P97876,
UniProt Related Accession:Q9NR55
Molecular Weight:14,468 Da
NCBI Full Name:Basic leucine zipper transcriptional factor ATF-like 3
NCBI Synonym Full Names:basic leucine zipper ATF-like transcription factor 3
NCBI Official Symbol:BATF3  
NCBI Official Synonym Symbols:JDP1; SNFT; JUNDM1  
NCBI Protein Information:basic leucine zipper transcriptional factor ATF-like 3
UniProt Protein Name:Basic leucine zipper transcriptional factor ATF-like 3
UniProt Synonym Protein Names:21 kDa small nuclear factor isolated from T-cells; Jun dimerization protein p21SNFT
Protein Family:Basic leucine zipper transcriptional factor
UniProt Gene Name:BATF3  
UniProt Entry Name:BATF3_HUMAN
Anti-BATF3 Antibody (CAB14906)Western blot analysis of extracts of rat spleen, using BATF3 antibody (CAB14906) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
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