Cell Biology Antibodies 6

Anti-BAALC Antibody (CAB15513)

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SKU:
CAB15513
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-BAALC Antibody
Antibody SKU:CAB15513
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-145 of human BAALC (NP_079088.1).
Application:WB
Recommended Dilution:WB 1:200 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:Mouse brain, Mouse skeletal muscle, Rat brain, Rat skeletal muscle
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-145 of human BAALC (NP_079088.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MGCG GSRA DAIE PRYY ESWT RETE STWL TYTD SDAP PSAA APDS GPEA GGLH SGML EDGL PSNG VPRS TAPG GIPN PEKK TNCE TQCP NPQS LSSG PLTQ KQNG LQTT EAKR DAKR MPAK EVTI NVTD SIQQ MDRS RRIT KNCV N
Gene ID:79870
Uniprot:Q8WXS3
Cellular Location:Cytoplasm, Membrane
Calculated MW:5kDa/7kDa/8kDa/15kDa/19kDa
Observed MW:19kDa
Synonyms:BAALC
Background:This gene was identified by gene expression studies in patients with acute myeloid leukemia (AML). The gene is conserved among mammals and is not found in lower organisms. Tissues that express this gene develop from the neuroectoderm. Multiple alternatively spliced transcript variants that encode different proteins have been described for this gene; however, some of the transcript variants are found only in AML cell lines.
UniProt Protein Function:BAALC: May play a synaptic role at the postsynaptic lipid rafts by interacting with CAMK2A. 6 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 8q22.3

Cellular Component: cytoplasm

NCBI Summary:This gene was identified by gene expression studies in patients with acute myeloid leukemia (AML). The gene is conserved among mammals and is not found in lower organisms. Tissues that express this gene develop from the neuroectoderm. Multiple alternatively spliced transcript variants that encode different proteins have been described for this gene; however, some of the transcript variants are found only in AML cell lines. [provided by RefSeq, Jul 2008]
UniProt Code:Q8WXS3
NCBI GenInfo Identifier:74730996
NCBI Gene ID:79870
NCBI Accession:Q8WXS3.3
UniProt Secondary Accession:Q8WXS3,Q8WTP6, Q8WXS0, Q8WXS1, Q8WXS2, Q9HA93,
UniProt Related Accession:Q8WXS3
Molecular Weight:5,663 Da
NCBI Full Name:Brain and acute leukemia cytoplasmic protein
NCBI Synonym Full Names:brain and acute leukemia, cytoplasmic
NCBI Official Symbol:BAALC  
NCBI Protein Information:brain and acute leukemia cytoplasmic protein
UniProt Protein Name:Brain and acute leukemia cytoplasmic protein
Protein Family:Brain and acute leukemia cytoplasmic protein
UniProt Gene Name:BAALC  
UniProt Entry Name:BAALC_HUMAN
Anti-BAALC Antibody (CAB15513)Western blot analysis of extracts of various cell lines, using BAALC Rabbit pAb (CAB15513) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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