Cell Biology Antibodies 13

Anti-B4GAT1 Antibody (CAB17624)

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SKU:
CAB17624
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-B4GAT1 Antibody
Antibody SKU:CAB17624
Antibody Size:20uL, 50 uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 35-180 of human B4GAT1 (NP_006867.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 35-180 of human B4GAT1 (NP_006867.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:GLHG QEEQ DQYF EFFP PSPR SVDQ VKAQ LRTA LASG GVLD ASGD YRVY RGLL KTTM DPND VILA THAS VDNL LHLS GLLE RWEG PLSV SVFA ATKE EAQL ATVL AYAL SSHC PDMR ARVA MHLV CPSR YEAA VPDP REPG EFAL LR
Gene ID:11041
Uniprot:O43505
Cellular Location:
Calculated MW:
Observed MW:Refer to figures
Synonyms:B3GN-T1, B3GNT1, B3GNT6, BETA3GNTI, MDDGA13, iGAT, iGNT, B4GAT1
Background:This gene encodes a member of the beta-1, 3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein. It is essential for the synthesis of poly-N-acetyllactosamine, a determinant for the blood group i antigen. [provided by RefSeq, Jul 2008]
UniProt Protein Function:B4GAT1: Can initiate the synthesis or the elongation of the linear poly-N-acetyllactosaminoglycans.
UniProt Protein Details:

Protein type:Glycan Metabolism - glycosphingolipid biosynthesis - lacto and neolacto series; Transferase; EC 2.4.1.149; Glycan Metabolism - keratan sulfate biosynthesis; Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q13.2

Cellular Component: Golgi apparatus; Golgi membrane

Molecular Function:glucuronosyltransferase activity; N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity

Biological Process: keratan sulfate biosynthetic process; poly-N-acetyllactosamine biosynthetic process; protein amino acid O-linked mannosylation

Disease: Muscular Dystrophy-dystroglycanopathy (congenital With Brain And Eye Anomalies), Type A, 13

NCBI Summary:This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein. It is essential for the synthesis of poly-N-acetyllactosamine, a determinant for the blood group i antigen. [provided by RefSeq, Jul 2008]
UniProt Code:O43505
NCBI GenInfo Identifier:23396461
NCBI Gene ID:11041
NCBI Accession:O43505.1
UniProt Secondary Accession:O43505,Q4TTN0,
UniProt Related Accession:O43505
Molecular Weight:47,119 Da
NCBI Full Name:Beta-1,4-glucuronyltransferase 1
NCBI Synonym Full Names:beta-1,4-glucuronyltransferase 1
NCBI Official Symbol:B4GAT1  
NCBI Official Synonym Symbols:iGAT; iGNT; B3GNT1; B3GNT6; B3GN-T1; MDDGA13; BETA3GNTI  
NCBI Protein Information:beta-1,4-glucuronyltransferase 1
UniProt Protein Name:Beta-1,4-glucuronyltransferase 1
UniProt Synonym Protein Names:I-beta-1,3-N-acetylglucosaminyltransferase; iGnT; N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase; Poly-N-acetyllactosamine extension enzyme; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
UniProt Gene Name:B4GAT1  
UniProt Entry Name:B4GA1_HUMAN
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