Cell Biology Antibodies 13
Anti-B4GALT5 Antibody (CAB17590)
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- SKU:
- CAB17590
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-B4GALT5 Antibody |
| Antibody SKU: | CAB17590 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-160 of human B4GALT5 (NP_004767.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Rat |
| Positive Samples: | 293T |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-160 of human B4GALT5 (NP_004767.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | IGAQ VYEQ VLRS AYAK RNSS VNDS DYPL DLNH SETF LQTT TFLP EDFT YFAN HTCP ERLP SMKG PIDI NMSE IGMD YIHE LFSK DPTI KLGG HWKP SDCM P |
| Gene ID: | 9334 |
| Uniprot: | O43286 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 45KDa |
 | Western blot - B4GALT5 Rabbit pAb (CAB17590) |
| Synonyms: | B4Gal-T5, BETA4-GALT-IV, beta4Gal-T5, beta4GalT-V, gt-V, B4GALT5 |
| Background: | This gene is one of seven beta-1, 4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1, 4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The function of the enzyme encoded by this gene is not clear. This gene was previously designated as B4GALT4 but was renamed to B4GALT5. In the literature it is also referred to as beta4GalT2. [provided by RefSeq, Jul 2008] |
| UniProt Protein Function: | B4GALT5: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. Belongs to the glycosyltransferase 7 family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Transferase; Glycan Metabolism - O-glycan biosynthesis; EC 2.4.1.- Chromosomal Location of Human Ortholog: 20q13.1-q13.2 Cellular Component: Golgi membrane; integral to membrane Molecular Function:galactosyltransferase activity; metal ion binding Biological Process: carbohydrate metabolic process; cellular protein metabolic process; glycosaminoglycan metabolic process; keratan sulfate biosynthetic process; keratan sulfate metabolic process; O-glycan processing; post-translational protein modification; protein amino acid N-linked glycosylation via asparagine; protein amino acid O-linked glycosylation |
| NCBI Summary: | This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The function of the enzyme encoded by this gene is not clear. This gene was previously designated as B4GALT4 but was renamed to B4GALT5. In the literature it is also referred to as beta4GalT2. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O43286 |
| NCBI GenInfo Identifier: | 4757828 |
| NCBI Gene ID: | 9334 |
| NCBI Accession: | NP_004767.1 |
| UniProt Secondary Accession: | O43286,Q2M394, Q9UJQ8, E1P625, |
| UniProt Related Accession: | O43286 |
| Molecular Weight: | 45,119 Da |
| NCBI Full Name: | beta-1,4-galactosyltransferase 5 |
| NCBI Synonym Full Names: | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 |
| NCBI Official Symbol: | B4GALT5 |
| NCBI Official Synonym Symbols: | gt-V; B4Gal-T5; beta4Gal-T5; beta4GalT-V; BETA4-GALT-IV |
| NCBI Protein Information: | beta-1,4-galactosyltransferase 5 |
| UniProt Protein Name: | Beta-1,4-galactosyltransferase 5 |
| UniProt Synonym Protein Names: | Beta-1,4-GalT II; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 5; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 5 |
| Protein Family: | Beta-1,4-galactosyltransferase |
| UniProt Gene Name: | B4GALT5 |
| UniProt Entry Name: | B4GT5_HUMAN |
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