Cell Biology Antibodies 13
Anti-B3GNT3 Antibody (CAB17611)
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- SKU:
- CAB17611
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-B3GNT3 Antibody |
| Antibody SKU: | CAB17611 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-240 of human B3GNT3 (NP_055071.2). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | SGC-7901, 293T, Mouse stomach |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-240 of human B3GNT3 (NP_055071.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | YVRR ELLR RTWG RERK VRGL QLRL LFLV GTAS NPHE ARKV NRLL ELEA QTHG DILQ WDFH DSFF NLTL KQVL FLQW QETR CANA SFVL NGDD DVFA HTDN MVFY LQDH DPGR HLFV GQLI Q |
| Gene ID: | 10331 |
| Uniprot: | Q9Y2A9 |
| Cellular Location: | |
| Calculated MW: | 42kDa |
| Observed MW: | 43kDa |
 | Western blot - B3GNT3 Rabbit pAb (CAB17611) |
| Synonyms: | B3GAL-T8, B3GN-T3, B3GNT-3, HP10328, TMEM3, beta3Gn-T3, B3GNT3 |
| Background: | This gene encodes a member of the beta-1, 3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein and contains a signal anchor that is not cleaved. It prefers the substrates of lacto-N-tetraose and lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains and the biosynthesis of the backbone structure of dimeric sialyl Lewis a. It plays dominant roles in L-selectin ligand biosynthesis, lymphocyte homing and lymphocyte trafficking. [provided by RefSeq, Jul 2008] |
| UniProt Protein Function: | B3GNT3: Has a beta-1,3-N-acetylglucosaminyltransferase activity for type 2 oligosaccharides. Belongs to the glycosyltransferase 31 family. |
| UniProt Protein Details: | Protein type:Transferase; Membrane protein, integral; Glycan Metabolism - glycosphingolipid biosynthesis - lacto and neolacto series; EC 2.4.1.146 Chromosomal Location of Human Ortholog: 19p13.1 Cellular Component: Golgi membrane; integral to plasma membrane Molecular Function:beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity; N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity; UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity Biological Process: keratan sulfate biosynthetic process; O-glycan processing; poly-N-acetyllactosamine biosynthetic process |
| NCBI Summary: | This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein and contains a signal anchor that is not cleaved. It prefers the substrates of lacto-N-tetraose and lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains and the biosynthesis of the backbone structure of dimeric sialyl Lewis a. It plays dominant roles in L-selectin ligand biosynthesis, lymphocyte homing and lymphocyte trafficking. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9Y2A9 |
| NCBI GenInfo Identifier: | 37183028 |
| NCBI Gene ID: | 10331 |
| NCBI Accession: | AAQ89314.1 |
| UniProt Secondary Accession: | Q9Y2A9,Q6NWU9, Q6NXU9, Q8WWR6, Q9C0J2, B2RAS4, |
| UniProt Related Accession: | Q9Y2A9 |
| Molecular Weight: | 42,534 Da |
| NCBI Full Name: | B3GNT3 |
| NCBI Synonym Full Names: | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| NCBI Official Symbol: | B3GNT3 |
| NCBI Official Synonym Symbols: | TMEM3; B3GN-T3; B3GNT-3; HP10328; B3GAL-T8; beta3Gn-T3 |
| NCBI Protein Information: | N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3 |
| UniProt Protein Name: | N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3 |
| UniProt Synonym Protein Names: | Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase (EC:2.4.1.146 |
| Protein Family: | N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase |
| UniProt Gene Name: | B3GNT3 |
| UniProt Entry Name: | B3GN3_HUMAN |
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