Cell Biology Antibodies 18

Anti-B3GNT2 Antibody (CAB18418)

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SKU:
CAB18418
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-B3GNT2 Antibody
Antibody SKU:CAB18418
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:Recombinant protein of human B3GNT2.
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse
Positive Samples:
Immunogen:Recombinant protein of human B3GNT2.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:10678
Uniprot:Q9NY97
Cellular Location:
Calculated MW:
Observed MW:Refer to figures
Synonyms:3-Gn-T1, 3-Gn-T2, B3GN-T2, B3GNT, B3GNT-2, B3GNT1, BETA3GNT, BGNT2, BGnT-2, beta-1, beta3Gn-T1, beta3Gn-T2, B3GNT2
Background:
UniProt Protein Function:B3GNT2: Catalyzes the initiation and elongation of poly-N- acetyllactosamine chains. Belongs to the glycosyltransferase 31 family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Glycan Metabolism - glycosphingolipid biosynthesis - lacto and neolacto series; Cell development/differentiation; Glycan Metabolism - keratan sulfate biosynthesis; Transferase; Motility/polarity/chemotaxis; Membrane protein, integral; EC 2.4.1.-

Chromosomal Location of Human Ortholog: 2p15

Cellular Component: Golgi membrane; integral to membrane

Molecular Function:N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity; UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity

Biological Process: axon guidance; keratan sulfate biosynthetic process; O-glycan processing; poly-N-acetyllactosamine biosynthetic process; sensory perception of smell

NCBI Summary:This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein. It prefers the substrate of lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jan 2016]
UniProt Code:Q9NY97
NCBI GenInfo Identifier:9845238
NCBI Gene ID:10678
NCBI Accession:NP_006568.2
UniProt Secondary Accession:Q9NY97,Q54AC1, Q9NQQ9, Q9NQR0, Q9NUT9,
UniProt Related Accession:Q9NY97
Molecular Weight:
NCBI Full Name:N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2
NCBI Synonym Full Names:UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
NCBI Official Symbol:B3GNT2  
NCBI Official Synonym Symbols:B3GNT; BGNT2; B3GNT1; BGnT-2; beta-1; 3-Gn-T1; 3-Gn-T2; B3GN-T2; B3GNT-2; BETA3GNT; beta3Gn-T1; beta3Gn-T2  
NCBI Protein Information:N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2
UniProt Protein Name:N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2
UniProt Synonym Protein Names:Beta-1,3-N-acetylglucosaminyltransferase 1; BGnT-1; Beta-1,3-Gn-T1; Beta3Gn-T1; Beta-1,3-galactosyltransferase 7; Beta-1,3-GalTase 7; Beta3Gal-T7; Beta3GalT7; b3Gal-T7; Beta-3-Gx-T7; UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 7; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2; BGnT-2; Beta-1,3-Gn-T2; Beta-1,3-N-acetylglucosaminyltransferase 2; Beta3Gn-T2; UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 7
Protein Family:N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase
UniProt Gene Name:B3GNT2  
UniProt Entry Name:B3GN2_HUMAN
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system_update_altDatasheetHuman B3GNT2 Recombinant Protein B3GNT2 belongs to the beta-1,3-N-acetylglucosaminyltransferase family. It is a type II transmembrane protein which prefers the substrate