Cell Biology Antibodies 14
Anti-ATP6V1G1 Antibody (CAB17054)
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- SKU:
- CAB17054
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-ATP6V1G1 Antibody |
| Antibody SKU: | CAB17054 |
| Antibody Size: | 20uL, 50 uL |
| Application: | IHC |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 39-118 of human ATP6V1G1 (NP_004879.1). |
| Application: | IHC |
| Recommended Dilution: | IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 39-118 of human ATP6V1G1 (NP_004879.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | EAQA EIEQ YRLQ REKE FKAK EAAA LGSR GSCS TEVE KETQ EKMT ILQT YFRQ NRDE VLDN LLAF VCDI RPEI HENY RING |
| Gene ID: | 9550 |
| Uniprot: | O75348 |
| Cellular Location: | |
| Calculated MW: | 13kDa |
| Observed MW: | Refer to figures |
| Synonyms: | ATP6V1G1, ATP6G, ATP6G1, ATP6GL, ATP6J, Vma10 |
| Background: | This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of three V1 domain G subunit proteins. Pseudogenes of this gene have been characterized. |
| UniProt Protein Function: | ATP6V1G1: Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. Belongs to the V-ATPase G subunit family. |
| UniProt Protein Details: | Protein type:Vesicle; Hydrolase Chromosomal Location of Human Ortholog: 9q32 Cellular Component: cytosol; lysosomal membrane; plasma membrane Molecular Function:ATPase binding; protein binding Biological Process: insulin receptor signaling pathway; transferrin transport |
| NCBI Summary: | This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of three V1 domain G subunit proteins. Pseudogenes of this gene have been characterized. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O75348 |
| NCBI GenInfo Identifier: | 6226299 |
| NCBI Gene ID: | 9550 |
| NCBI Accession: | O75348.3 |
| UniProt Secondary Accession: | O75348,Q6IB33, |
| UniProt Related Accession: | O75348 |
| Molecular Weight: | 13,758 Da |
| NCBI Full Name: | V-type proton ATPase subunit G 1 |
| NCBI Synonym Full Names: | ATPase H+ transporting V1 subunit G1 |
| NCBI Official Symbol: | ATP6V1G1 |
| NCBI Official Synonym Symbols: | ATP6G; ATP6J; Vma10; ATP6G1; ATP6GL |
| NCBI Protein Information: | V-type proton ATPase subunit G 1 |
| UniProt Protein Name: | V-type proton ATPase subunit G 1 |
| UniProt Synonym Protein Names: | V-ATPase 13 kDa subunit 1; Vacuolar proton pump subunit G 1; Vacuolar proton pump subunit M16 |
| Protein Family: | V-type proton ATPase |
| UniProt Gene Name: | ATP6V1G1 |
| UniProt Entry Name: | VATG1_HUMAN |
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