Anti-ATP4B Antibody (CAB19280)
- SKU:
- CAB19280
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- ATP4B
- Synonyms:
- ATP6B
- Synonyms:
- ATPase H+/K+ transporting beta subunit
- Research Area:
- Cell Biology
Description
| Product Name: | ATP4B Rabbit mAb |
| Product Code: | CAB19280 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | ATP4B, ATP6B, ATPase H+/K+ transporting beta subunit |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human ATP4B. |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HT-29, HepG2, Mouse stomach, Rat testis |
| Immunogen: | Recombinant protein of human ATP4B. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 496 |
| Uniprot: | P51164 |
| Cellular Location: | Cell membrane, Single-pass type II membrane protein |
| Calculated MW: | 55kDa |
| Observed MW: | 50KDa |
| UniProt Protein Function: | ATP4B: belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes the beta subunit of the gastric H+, K+-ATPase. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 13q34 Cellular Component: plasma membrane Molecular Function:hydrogen:potassium-exchanging ATPase activity; protein binding |
| NCBI Summary: | The protein encoded by this gene belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes the beta subunit of the gastric H+, K+-ATPase. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P51164 |
| NCBI GenInfo Identifier: | 1703461 |
| NCBI Gene ID: | 496 |
| NCBI Accession: | P51164.1 |
| UniProt Secondary Accession: | P51164,B1B0N8, |
| UniProt Related Accession: | P51164 |
| Molecular Weight: | 33,367 Da |
| NCBI Full Name: | Potassium-transporting ATPase subunit beta |
| NCBI Synonym Full Names: | ATPase H+/K+ transporting beta subunit |
| NCBI Official Symbol: | ATP4B |
| NCBI Official Synonym Symbols: | ATP6B |
| NCBI Protein Information: | potassium-transporting ATPase subunit beta |
| UniProt Protein Name: | Potassium-transporting ATPase subunit beta |
| UniProt Synonym Protein Names: | Gastric H(+)/K(+) ATPase subunit beta; Proton pump beta chain |
| Protein Family: | Potassium-transporting ATPase |
| UniProt Gene Name: | ATP4B |
| UniProt Entry Name: | ATP4B_HUMAN |
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