Cell Biology Antibodies 15
Anti-ATP2B1 Antibody (CAB18688)
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- SKU:
- CAB18688
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-ATP2B1 Antibody |
| Antibody SKU: | CAB18688 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 250-350 of human ATP2B1 (NP_001673.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | Mouse brain |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 250-350 of human ATP2B1 (NP_001673.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 490 |
| Uniprot: | P20020 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 140kDa |
 | Western blot - ATP2B1 Rabbit pAb (CAB18688) |
| Synonyms: | |
| Background: |
| NCBI Summary: | The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 1. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P20020 |
| NCBI GenInfo Identifier: | 1476413389 |
| NCBI Gene ID: | 490 |
| NCBI Accession: | P20020.4 |
| UniProt Related Accession: | P20020 |
| Molecular Weight: | |
| NCBI Full Name: | Plasma membrane calcium-transporting ATPase 1 |
| NCBI Synonym Full Names: | ATPase plasma membrane Ca2+ transporting 1 |
| NCBI Official Symbol: | ATP2B1 |
| NCBI Official Synonym Symbols: | PMCA1; PMCA1kb |
| NCBI Protein Information: | plasma membrane calcium-transporting ATPase 1 |
| UniProt Protein Name: | Plasma membrane calcium-transporting ATPase 1 |
| UniProt Synonym Protein Names: | Plasma membrane calcium ATPase isoform 1; Plasma membrane calcium pump isoform 1 |
| Protein Family: | Plasma membrane calcium-transporting ATPase |
| UniProt Gene Name: | ATP2B1 |
| UniProt Entry Name: | AT2B1_HUMAN |
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