Anti-ATP1B3 Antibody (CAB19637)

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SKU:
CAB19637

Description

Product Name:ATP1B3 Rabbit mAb
Product Code:CAB19637
Size:20uL, 50uL, 100uL
Synonyms:ATPB-3, CD298
Applications:WB, IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human ATP1B3
Applications:WB, IHC
Recommended Dilutions:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:293T, U-87MG, Mouse lung, Mouse testis, Mouse brain, Rat lung, Rat testis, Rat spleen
Immunogen:A synthesized peptide derived from human ATP1B3
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:483
Uniprot:P54709
Calculated MW:37kDa
Observed MW:32KDa
UniProt Protein Function:ATP1B3: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known. Belongs to the X(+)/potassium ATPases subunit beta family.Protein type: Membrane protein, integral; TransporterChromosomal Location of Human Ortholog: 3q23Cellular Component: plasma membrane; sodium:potassium-exchanging ATPase complexMolecular Function: ATPase activator activity; ATPase binding; sodium:potassium-exchanging ATPase activityBiological Process: cellular potassium ion homeostasis; cellular sodium ion homeostasis; leukocyte migration; positive regulation of ATPase activity; potassium ion import; protein stabilization; transport
UniProt Protein Details:
NCBI Summary:The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene exists for this gene, and it is located on chromosome 2. [provided by RefSeq, Jul 2008]
UniProt Code:P54709
NCBI GenInfo Identifier:1703470
NCBI Gene ID:483
NCBI Accession:P54709.1
UniProt Secondary Accession:P54709,B7Z1N7
UniProt Related Accession:P54709
Molecular Weight:21,713 Da
NCBI Full Name:Sodium/potassium-transporting ATPase subunit beta-3
NCBI Synonym Full Names:ATPase Na+/K+ transporting subunit beta 3
NCBI Official Symbol:ATP1B3  
NCBI Official Synonym Symbols:CD298; ATPB-3  
NCBI Protein Information:sodium/potassium-transporting ATPase subunit beta-3
UniProt Protein Name:Sodium/potassium-transporting ATPase subunit beta-3
UniProt Synonym Protein Names:Sodium/potassium-dependent ATPase subunit beta-3; ATPB-3; CD_antigen: CD298
Protein Family:
UniProt Gene Name:ATP1B3  
UniProt Entry Name:AT1B3_HUMAN
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Additional Information

Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
ATPB-3
Synonyms:
CD298
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