Name: Anti-ATG3 Antibody (CAB19594)
Brand: Autophagy Antibodies
SKU: CAB19594
Availability: OutOfStock

Antibody Name:	Anti-ATG3 Antibody
Antibody SKU:	CAB19594
Antibody Size:	20uL, 50uL, 100uL
Application:	WB IHC
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	A synthesized peptide derived from human Apg3 (Atg3).

Application:	WB IHC
Recommended Dilution:	WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:	Human, Mouse, Rat
Positive Samples:	Jurkat, U-87MG, K-562, Mouse brain, Mouse testis, Rat testis

Immunogen:	A synthesized peptide derived from human Apg3 (Atg3).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	Email for sequence
Gene ID:	64422
Uniprot:	Q9NT62
Cellular Location:
Calculated MW:	40kDa
Observed MW:	40KDa

Western blot - ATG3 Rabbit mAb (CAB19594)

Synonyms:

ATG3, APG3, APG3-LIKE, APG3L, PC3-96

Background:

This gene encodes a ubiquitin-like-conjugating enzyme and is a component of ubiquitination-like systems involved in autophagy, the process of degradation, turnover and recycling of cytoplasmic constituents in eukaryotic cells. This protein is known to play a role in regulation of autophagy during cell death. A pseudogene of this gene is located on chromosome 20. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]

UniProt Protein Function:	ATG3: an E2-like enzyme essential for Apg8p lipidation.
UniProt Protein Details:	Protein type:Ubiquitin conjugating system; Enzyme, cellular metabolism; Autophagy; EC 6.3.2.- Chromosomal Location of Human Ortholog: 3q13.2 Cellular Component: cytoplasmic ubiquitin ligase complex; cytosol Molecular Function:APG12 conjugating enzyme activity; APG8 conjugating enzyme activity; enzyme binding; protein binding; small conjugating protein ligase activity Biological Process: autophagic vacuole formation; macroautophagy; mitochondrial fragmentation during apoptosis; mitochondrion degradation; protein modification process; protein targeting to membrane; protein ubiquitination
NCBI Summary:	This gene encodes a ubiquitin-like-conjugating enzyme and is a component of ubiquitination-like systems involved in autophagy, the process of degradation, turnover and recycling of cytoplasmic constituents in eukaryotic cells. This protein is known to play a role in regulation of autophagy during cell death. A pseudogene of this gene is located on chromosome 20. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
UniProt Code:	Q9NT62
NCBI GenInfo Identifier:	61212142
NCBI Gene ID:	64422
NCBI Accession:	Q9NT62.1
UniProt Secondary Accession:	Q9NT62,Q6PKC5, Q9H6L9,
UniProt Related Accession:	Q9NT62
Molecular Weight:	35,467 Da
NCBI Full Name:	Ubiquitin-like-conjugating enzyme ATG3
NCBI Synonym Full Names:	autophagy related 3
NCBI Official Symbol:	ATG3
NCBI Official Synonym Symbols:	APG3; APG3L; PC3-96; APG3-LIKE
NCBI Protein Information:	ubiquitin-like-conjugating enzyme ATG3
UniProt Protein Name:	Ubiquitin-like-conjugating enzyme ATG3
UniProt Synonym Protein Names:	Autophagy-related protein 3; APG3-like; hApg3; Protein PC3-96
Protein Family:	Autophagy-related protein
UniProt Gene Name:	ATG3
UniProt Entry Name:	ATG3_HUMAN