Anti-ATAD2 Antibody (CAB19792)
- SKU:
- CAB19792
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- ANCCA
- Synonyms:
- CT137
- Synonyms:
- PRO2000
Description
| Product Name: | ATAD2 Rabbit mAb |
| Product Code: | CAB19792 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | ANCCA, CT137, PRO2000 |
| Applications: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human ATAD2 |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | MCF7, K-562 |
| Immunogen: | A synthesized peptide derived from human ATAD2 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 29028 |
| Uniprot: | Q6PL18 |
| Calculated MW: | 180kDa |
| Observed MW: | 180KDa |
| UniProt Protein Function: | ATAD2: a member of the AAA ATPase family. Contains a bromodomain, a domain known to interact specifically with acetylated lysine. Two alternatively spliced isoforms of the human protein have been reported. |
| UniProt Protein Details: | Protein type:EC 3.6.1.3; Hydrolase; Cancer Testis Antigen (CTA) Chromosomal Location of Human Ortholog: 8q24.13 Cellular Component: nucleoplasm; nucleus Molecular Function:ATPase activity; chromatin binding; histone binding Biological Process: negative regulation of chromatin silencing; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent |
| NCBI Summary: | A large family of ATPases has been described, whose key feature is that they share a conserved region of about 220 amino acids that contains an ATP-binding site. The proteins that belong to this family either contain one or two AAA (ATPases Associated with diverse cellular Activities) domains. AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes. The protein encoded by this gene contains two AAA domains, as well as a bromodomain. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q6PL18 |
| NCBI GenInfo Identifier: | 74762365 |
| NCBI Gene ID: | 29028 |
| NCBI Accession: | Q6PL18.1 |
| UniProt Secondary Accession: | Q6PL18,Q14CR1, Q658P2, Q68CQ0, Q6PJV6, Q8N890, Q9UHS5 |
| UniProt Related Accession: | Q6PL18 |
| Molecular Weight: | 47,986 Da |
| NCBI Full Name: | ATPase family AAA domain-containing protein 2 |
| NCBI Synonym Full Names: | ATPase family, AAA domain containing 2 |
| NCBI Official Symbol: | ATAD2 |
| NCBI Official Synonym Symbols: | ANCCA; CT137; PRO2000 |
| NCBI Protein Information: | ATPase family AAA domain-containing protein 2 |
| UniProt Protein Name: | ATPase family AAA domain-containing protein 2 |
| UniProt Synonym Protein Names: | AAA nuclear coregulator cancer-associated protein; ANCCA |
| Protein Family: | ATPase family AAA domain-containing protein |
| UniProt Gene Name: | ATAD2 |
| UniProt Entry Name: | ATAD2_HUMAN |
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