Cell Biology Antibodies 7

Anti-ARSG Antibody (CAB17102)

(No reviews yet) Write a Review
SKU:
CAB17102
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-ARSG Antibody
Antibody SKU:CAB17102
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 376-525 of human ARSG (NP_001254656.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 376-525 of human ARSG (NP_001254656.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:AQAS LPQG RRFD GVDV SEVL FGRS QPGH RVLF HPNS GAAG EFGA LQTV RLER YKAF YITG GARA CDGS TGPE LQHK FPLI FNLE DDTA EAVP LERG GAEY QAVL PEVR KVLA DVLQ DIAN DNIS SADY TQDP SVTP CCNP YQIA CRCQ AA
Gene ID:22901
Uniprot:Q96EG1
Cellular Location:
Calculated MW:57kDa
Observed MW:Refer to figures
Synonyms:ARSG
Background:The protein encoded by this gene belongs to the sulfatase enzyme family. Sulfatases hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules. This protein displays arylsulfatase activity at acidic pH, as is typical of lysosomal sulfatases, and has been shown to localize in the lysosomes. Alternatively spliced transcript variants have been found for this gene.
UniProt Protein Function:ARSG: Displays arylsulfatase activity at acidic pH with pseudosubstrates, such as p-nitrocatechol sulfate and also, but with lower activity, p-nitrophenyl sulfate and 4- methylumbelliferyl sulfate. Belongs to the sulfatase family.
UniProt Protein Details:

Protein type:Kinase, other; EC 3.1.6.-; Hydrolase; Secreted; Secreted, signal peptide; Endoplasmic reticulum

Chromosomal Location of Human Ortholog: 17q24.2

Cellular Component: endoplasmic reticulum; endoplasmic reticulum lumen; extracellular space; lysosome

Molecular Function:arylsulfatase activity; metal ion binding

Biological Process: cellular protein metabolic process; glycosphingolipid metabolic process; post-translational protein modification; sphingolipid metabolic process; sulfur metabolic process

NCBI Summary:The protein encoded by this gene belongs to the sulfatase enzyme family. Sulfatases hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules. This protein displays arylsulfatase activity at acidic pH, as is typical of lysosomal sulfatases, and has been shown to localize in the lysosomes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012]
UniProt Code:Q96EG1
NCBI GenInfo Identifier:74731559
NCBI Gene ID:22901
NCBI Accession:Q96EG1.1
UniProt Secondary Accession:Q96EG1,Q6UXF2, Q9Y2K4,
UniProt Related Accession:Q96EG1
Molecular Weight:57,061 Da
NCBI Full Name:Arylsulfatase G
NCBI Synonym Full Names:arylsulfatase G
NCBI Official Symbol:ARSG  
NCBI Protein Information:arylsulfatase G
UniProt Protein Name:Arylsulfatase G
Protein Family:Arylsulfatase
UniProt Gene Name:ARSG  
UniProt Entry Name:ARSG_HUMAN
Anti-ARSG Antibody (CAB17102)Western blot analysis of extracts of various cell lines, using ARSG antibody (CAB17102) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
View AllClose

0 Reviews

View AllClose

Related Products

ARSG Polyclonal Antibody

ARSG Polyclonal Antibody

ARSG Polyclonal AntibodyThe product page for this antibody is being prepared. If you have a question please don't hesitate to get in touch!