Cell Biology Antibodies 5
Anti-ARSF Antibody (CAB15031)
- SKU:
- CAB15031
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Antibody Name: | Anti-ARSF Antibody |
Antibody SKU: | CAB15031 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB IF |
Reactivity: | Human |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human ARSF (NP_004033.2). |
Application: | WB IF |
Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
Reactivity: | Human |
Positive Samples: |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human ARSF (NP_004033.2). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | MRPR RPLV FMSL VCAL LNTC QAHR VHDD KPNI VLIM VDDL GIGD LGCY GNDT MRTP HIDR LARE GVRL TQHI SAAS LCSP SRSA FLTG RYPI RSGM VSSG NRRV IQNL AVPA GLPL NETT LAAL LKKQ GYST GLIG KWHQ GLNC DSRS DQCH HPYN YGFD YYYG MPFT LVDS CWPD PSRN TELA FESQ LWLC VQLV AIAI |
Gene ID: | 416 |
Uniprot: | P54793 |
Cellular Location: | Secreted |
Calculated MW: | 65kDa |
Observed MW: | Refer to figures |
Synonyms: | ARSF, ASF |
Background: | This gene is a member of the sulfatase family, and more specifically, the arylsulfatase subfamily. Members of the subfamily share similarity in sequence and splice sites, and are clustered together on chromosome X, suggesting that they are derived from recent gene duplication events. Sulfatases are essential for the correct composition of bone and cartilage matrix. The activity of this protein, unlike that of arylsulfatase E, is not inhibited by warfarin. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
UniProt Protein Function: | ARSF: a member of the sulfatase family, and more specifically, the arylsulfatase subfamily. Members of the subfamily share similarity in sequence and splice sites, and are clustered together on chromosome X, suggesting that they are derived from recent gene duplication events. Sulfatases are essential for the correct composition of bone and cartilage matrix. The activity of this protein, unlike that of arylsulfatase E, is not inhibited by warfarin. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Jan 2011] |
UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted; EC 3.1.6.-; Hydrolase Chromosomal Location of Human Ortholog: Xp22.3 Cellular Component: endoplasmic reticulum lumen Molecular Function:arylsulfatase activity Biological Process: glycosphingolipid metabolic process; post-translational protein modification |
NCBI Summary: | This gene is a member of the sulfatase family, and more specifically, the arylsulfatase subfamily. Members of the subfamily share similarity in sequence and splice sites, and are clustered together on chromosome X, suggesting that they are derived from recent gene duplication events. Sulfatases are essential for the correct composition of bone and cartilage matrix. The activity of this protein, unlike that of arylsulfatase E, is not inhibited by warfarin. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Jan 2011] |
UniProt Code: | P54793 |
NCBI GenInfo Identifier: | 259016386 |
NCBI Gene ID: | 416 |
NCBI Accession: | P54793.4 |
UniProt Secondary Accession: | P54793,Q8TCC5, |
UniProt Related Accession: | P54793 |
Molecular Weight: | 65,940 Da |
NCBI Full Name: | Arylsulfatase F |
NCBI Synonym Full Names: | arylsulfatase F |
NCBI Official Symbol: | ARSF |
NCBI Official Synonym Symbols: | ASF |
NCBI Protein Information: | arylsulfatase F |
UniProt Protein Name: | Arylsulfatase F |
Protein Family: | Arylsulfatase |
UniProt Gene Name: | ARSF |
UniProt Entry Name: | ARSF_HUMAN |
Immunofluorescence analysis of U2OS cells using ARSF antibody (CAB15031) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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