Cell Biology Antibodies 12

Anti-ARMCX3 Antibody (CAB9719)

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SKU:
CAB9719
Product Type:
Antibody
Applications:
WB
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-ARMCX3 Antibody
Antibody SKU:CAB9719
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 40-140 of human ARMCX3 (NP_057691.1).
Application:WB
Recommended Dilution:WB 1:200 - 1:1000
Reactivity:Human
Positive Samples:LO2, U-87MG
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 40-140 of human ARMCX3 (NP_057691.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:EGGS GDVD DAGD CSGA RYND WSDD DDDS NESK SIVW YPPW ARIG TEAG TRAR ARAR ARAT RARR AVQK RASP NSDD TVLS PQEL QKVL CLVE MSEK PYIL E
Gene ID:51566
Uniprot:Q9UH62
Cellular Location:Membrane, Single-pass membrane protein
Calculated MW:42kDa
Observed MW:39kDa
Synonyms:ARMCX3, ALEX3, GASP6, dJ545K15.2
Background:This gene encodes a member of the ALEX family of proteins which may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and a single Armadillo (arm) repeat. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with other family members on the X chromosome. Three transcript variants encoding the same protein have been identified for this gene.
UniProt Protein Function:ARMCX3: an armadillo-repeat protein. Armadillo proteins function in multiple processes including intracellular signalling, cytoskeletal regulation, and transcriptional regulation. Armadillo proteins include beta-catenin, the junctional plaque protein plakoglobin, the adenomatous polyposis coli (APC) tumour suppressor protein, and the nuclear transport factor importin-alpha.
UniProt Protein Details:

Protein type:Mitochondrial; Membrane protein, integral

Chromosomal Location of Human Ortholog: Xq22.1

NCBI Summary:This gene encodes a member of the ALEX family of proteins which may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and a single Armadillo (arm) repeat. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with other family members on the X chromosome. Three transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
UniProt Code:Q9UH62
NCBI GenInfo Identifier:74753322
NCBI Gene ID:51566
NCBI Accession:Q9UH62.1
UniProt Secondary Accession:Q9UH62,Q53HC6, Q7LCF5, Q9NPE4,
UniProt Related Accession:Q9UH62
Molecular Weight:42,501 Da
NCBI Full Name:Armadillo repeat-containing X-linked protein 3
NCBI Synonym Full Names:armadillo repeat containing, X-linked 3
NCBI Official Symbol:ARMCX3  
NCBI Official Synonym Symbols:ALEX3; GASP6; dJ545K15.2  
NCBI Protein Information:armadillo repeat-containing X-linked protein 3
UniProt Protein Name:Armadillo repeat-containing X-linked protein 3
UniProt Synonym Protein Names:ARM protein lost in epithelial cancers on chromosome X 3; Protein ALEX3
Protein Family:Armadillo repeat-containing X-linked protein
UniProt Gene Name:ARMCX3  
UniProt Entry Name:ARMX3_HUMAN
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