Cell Death Antibodies 1

Anti-ARL6IP1 Antibody (CAB17107)

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SKU:
CAB17107
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Death

Description

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Antibody Name:Anti-ARL6IP1 Antibody
Antibody SKU:CAB17107
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ARL6IP1 (NP_055976.1).
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100
Reactivity:Human, Mouse, Rat
Positive Samples:
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ARL6IP1 (NP_055976.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MAEG DNRS TNLL AAET ASLE EQLQ GWGE VMLM ADKV LRWE RAWF PPAI MGVV SLVF LIIY YLDP SVLS GVSC FVMF LCLA DYLV PILA PRIF GSNK WTTE
Gene ID:23204
Uniprot:Q15041
Cellular Location:
Calculated MW:
Observed MW:Refer to figures
Synonyms:ARL6IP1, AIP1, ARL6IP, ARMER, SPG61
Background:This gene belongs to the ARL6ip family and encodes a transmembrane protein that is predominantly localized to intracytoplasmic membranes. It is highly expressed in early myeloid progenitor cells and thought to be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Mutations in this gene are associated with spastic paraplegia 61 (SPG61). Alternatively spliced transcript variants have been found for this gene.
UniProt Protein Function:ARL6IP: May be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Belongs to the ARL6ip family.
UniProt Protein Details:

Protein type:Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 16p12-p11.2

Cellular Component: membrane; integral to membrane; translocon complex; cytosol

Molecular Function:protein binding

Biological Process: cotranslational protein targeting to membrane

Disease: Spastic Paraplegia 61, Autosomal Recessive

NCBI Summary:This gene belongs to the ARL6ip family and encodes a transmembrane protein that is predominantly localized to intracytoplasmic membranes. It is highly expressed in early myeloid progenitor cells and thought to be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Mutations in this gene are associated with spastic paraplegia 61 (SPG61). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015]
UniProt Code:Q15041
NCBI GenInfo Identifier:14424435
NCBI Gene ID:23204
NCBI Accession:Q15041.2
UniProt Secondary Accession:Q15041,B7Z6S5, B7Z791, F5GXP4,
UniProt Related Accession:Q15041
Molecular Weight:17,158 Da
NCBI Full Name:ADP-ribosylation factor-like protein 6-interacting protein 1
NCBI Synonym Full Names:ADP-ribosylation factor-like 6 interacting protein 1
NCBI Official Symbol:ARL6IP1  
NCBI Official Synonym Symbols:AIP1; ARMER; SPG61; ARL6IP  
NCBI Protein Information:ADP-ribosylation factor-like protein 6-interacting protein 1; aip-1; ARL-6-interacting protein 1; apoptotic regulator in the membrane of the endoplasmic reticulum
UniProt Protein Name:ADP-ribosylation factor-like protein 6-interacting protein 1
Protein Family:ADP-ribosylation factor-like protein 6-interacting protein
UniProt Gene Name:ARL6IP1  
UniProt Entry Name:AR6P1_HUMAN
Anti-ARL6IP1 Antibody (CAB17107)Western blot analysis of extracts of various cell lines, using ARL6IP1 antibody (CAB17107) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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