Cell Biology Antibodies 14

Anti-ARL4A Antibody (CAB17071)

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SKU:
CAB17071
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-ARL4A Antibody
Antibody SKU:CAB17071
Antibody Size:20uL, 50uL, 100uL
Application:IHC IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 121-200 of human ARL4A (NP_001032241.1).
Application:IHC IF
Recommended Dilution:IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 121-200 of human ARL4A (NP_001032241.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:ISEN QGVP VLIV ANKQ DLRN SLSL SEIE KLLA MGEL SSST PWHL QPTC AIIG DGLK EGLE KLHD MIIK RRKM LRQQ KKKR
Gene ID:10124
Uniprot:P40617
Cellular Location:
Calculated MW:22kDa
Observed MW:Refer to figures
Anti-ARL4A Antibody (CAB17071)Immunohistochemistry - ARL4A Polyclonal Antibody (CAB17071)
Synonyms:ARL4A, ARL4
Background:ADP-ribosylation factor-like 4A is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL4A is similar to ARL4C and ARL4D and each has a nuclear localization signal and an unusually high guaninine nucleotide exchange rate. ARL4A is located in both the nuclear and extranuclear cell compartments. Multiple transcript variants encoding the same protein have been found for this gene.
UniProt Protein Function:ARL4A: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form. Belongs to the small GTPase superfamily. Arf family.
UniProt Protein Details:

Protein type:Nucleolus; G protein, monomeric; G protein, monomeric, ARF

Chromosomal Location of Human Ortholog: 7p21.3

Cellular Component: cytoplasm; plasma membrane; nucleolus; nucleus

Molecular Function:protein binding; GTP binding

Biological Process: small GTPase mediated signal transduction; brown fat cell differentiation

NCBI Summary:ADP-ribosylation factor-like 4A is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL4A is similar to ARL4C and ARL4D and each has a nuclear localization signal and an unusually high guaninine nucleotide exchange rate. ARL4A is located in both the nuclear and extranuclear cell compartments. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Code:P40617
NCBI GenInfo Identifier:81295813
NCBI Gene ID:10124
NCBI Accession:NP_001032241
UniProt Secondary Accession:P40617,P80418, Q49AF5, A4D119,
UniProt Related Accession:P40617
Molecular Weight:22,615 Da
NCBI Full Name:ADP-ribosylation factor-like protein 4A
NCBI Synonym Full Names:ADP-ribosylation factor-like 4A
NCBI Official Symbol:ARL4A  
NCBI Official Synonym Symbols:ARL4  
NCBI Protein Information:ADP-ribosylation factor-like protein 4A
UniProt Protein Name:ADP-ribosylation factor-like protein 4A
UniProt Gene Name:ARL4A  
UniProt Entry Name:ARL4A_HUMAN
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