Cell Biology Antibodies 13
Anti-ARHGEF26 Antibody (CAB17677)
(No reviews yet)
Write a Review
- SKU:
- CAB17677
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-ARHGEF26 Antibody |
| Antibody SKU: | CAB17677 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 592-871 of human ARHGEF26 (NP_056410.3). |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse lung, Mouse brain, Rat lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 592-871 of human ARHGEF26 (NP_056410.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | ICQK TPKD SPKY EVCK RALK EVSK LVRL CNEG ARKM ERTE MMYT INSQ LEFK IKPF PLVS SSRW LVKR GELT AYVE DTVL FSRR TSKQ QVYF FLFN DVLI ITKK KSEE SYNV NDYS LRDQ LLVE SCDN EELN SSPG KNSS TMLY SRQS SASH LFTL TVLS NHAN EKVE MLLG AETQ SERA RWIT ALGH SSGK PPAD RTSL TQVE IVRS FTAK QPDE LSLQ VADV VLIY QRVS DGWY EGER LRDG ERGW FPME CAKE ITCQ ATID KNVE RMGR LLGL ETNV |
| Gene ID: | 26084 |
| Uniprot: | Q96DR7 |
| Cellular Location: | |
| Calculated MW: | 48kDa/88kDa/97kDa |
| Observed MW: | 102kDa |
 | Western blot - ARHGEF26 Polyclonal Antibody (CAB17677) |
| Synonyms: | ARHGEF26, CSGEF, HMFN1864, SGEF |
| Background: | This gene encodes a member of the Rho-guanine nucleotide exchange factor (Rho-GEF) family. These proteins regulate Rho GTPases by catalyzing the exchange of GDP for GTP. The encoded protein specifically activates RhoG and plays a role in the promotion of macropinocytosis. Underexpression of the encoded protein may be a predictive marker of chemoresistant disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011] |
| UniProt Protein Function: | SGEF: Activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB, which induces cytoskeleton rearrangements and promotes bacterial entry. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:GEFs; GEFs, Rac/Rho Chromosomal Location of Human Ortholog: 3q25.2 |
| NCBI Summary: | This gene encodes a member of the Rho-guanine nucleotide exchange factor (Rho-GEF) family. These proteins regulate Rho GTPases by catalyzing the exchange of GDP for GTP. The encoded protein specifically activates RhoG and plays a role in the promotion of macropinocytosis. Underexpression of the encoded protein may be a predictive marker of chemoresistant disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011] |
| UniProt Code: | Q96DR7 |
| NCBI GenInfo Identifier: | 317373555 |
| NCBI Gene ID: | 26084 |
| NCBI Accession: | Q96DR7.4 |
| UniProt Secondary Accession: | Q96DR7,Q68CL1, Q6AZ96, Q6Q8Q8, Q96AW8, Q96DR6, Q9H9D7 Q9H9R2, Q9UFW5, B3KVP8, E9PBD0, |
| UniProt Related Accession: | Q96DR7 |
| Molecular Weight: | 88,134 Da |
| NCBI Full Name: | Rho guanine nucleotide exchange factor 26 |
| NCBI Synonym Full Names: | Rho guanine nucleotide exchange factor 26 |
| NCBI Official Symbol: | ARHGEF26 |
| NCBI Official Synonym Symbols: | SGEF; CSGEF; HMFN1864 |
| NCBI Protein Information: | rho guanine nucleotide exchange factor 26 |
| UniProt Protein Name: | Rho guanine nucleotide exchange factor 26 |
| UniProt Synonym Protein Names: | SH3 domain-containing guanine exchange factor |
| Protein Family: | Rho guanine nucleotide exchange factor |
| UniProt Gene Name: | ARHGEF26 |
| UniProt Entry Name: | ARHGQ_HUMAN |
Related Products
Human anti-EPO antibody(anti-Erythropoietin antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक
Human Anti-DSG3 antibody(anti-Desmoglein-3 antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक
Human anti-ASGPR antibody(anti asialoglyco protein receptor antibody)ELISA Kit
OverviewProduct Name:Human anti-ASGPR antibody(anti asialoglyco protein receptor antibody)ELISA KitProduct Code:AEFI00360Size:96TAlias:a