Cell Biology Antibodies 11
Anti-ARHGAP44 Antibody (CAB7357)
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- SKU:
- CAB7357
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-ARHGAP44 Antibody |
| Antibody SKU: | CAB7357 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 666-772 of human ARHGAP44 (NP_055674.4). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | MCF7, 293T, Mouse brain, Mouse heart, Mouse lung, Rat heart, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 666-772 of human ARHGAP44 (NP_055674.4). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MADQ SAGQ PSPV SLSP TPPS TPSP YGLS YPQG YSLA SGQL SPAA APPL ASPS VFTS TLSK SRPT PKPR QRPT LPPP QPPT VNLS ASSP QSTE APML DGMS PGES MST |
| Gene ID: | 9912 |
| Uniprot: | Q17R89 |
| Cellular Location: | Cell junction, Cell projection, Recycling endosome, dendritic spine, synapse |
| Calculated MW: | 83kDa/88kDa/89kDa |
| Observed MW: | 110kDa |
| Synonyms: | ARHGAP44, NPC-A-10, RICH2 |
| Background: |
| UniProt Protein Function: | RICH2: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Acts as a GTPase activitor in vitro for CDC42 and RAC1. |
| UniProt Protein Details: | Protein type:GAPs; GAPs, Rac/Rho Chromosomal Location of Human Ortholog: 17p12 Cellular Component: recycling endosome; dendritic spine; synapse; cytosol; cell junction Molecular Function:protein binding; phospholipid binding; GTPase activator activity Biological Process: regulation of small GTPase mediated signal transduction; exocytosis; small GTPase mediated signal transduction; positive regulation of GTPase activity |
| UniProt Code: | Q17R89 |
| NCBI GenInfo Identifier: | 121948837 |
| NCBI Gene ID: | 9912 |
| NCBI Accession: | Q17R89.1 |
| UniProt Secondary Accession: | Q17R89,O75160, Q7Z5Z7, Q9Y4Q4, A6NCP5, A8MQB2, |
| UniProt Related Accession: | Q17R89 |
| Molecular Weight: | 818 |
| NCBI Full Name: | Rho GTPase-activating protein 44 |
| NCBI Synonym Full Names: | Rho GTPase activating protein 44 |
| NCBI Official Symbol: | ARHGAP44 |
| NCBI Official Synonym Symbols: | RICH2; NPC-A-10 |
| NCBI Protein Information: | rho GTPase-activating protein 44; RICH-2; rho GTPase-activating protein RICH2; Rho-type GTPase-activating protein RICH2; RhoGAP interacting with CIP4 homologs protein 2 |
| UniProt Protein Name: | Rho GTPase-activating protein 44 |
| UniProt Synonym Protein Names: | NPC-A-10; Rho-type GTPase-activating protein RICH2; RhoGAP interacting with CIP4 homologs protein 2; RICH-2 |
| Protein Family: | Rho GTPase-activating protein |
| UniProt Gene Name: | ARHGAP44 |
| UniProt Entry Name: | RHG44_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ARHGAP44 antibody (CAB7357) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
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