Cell Biology Antibodies 17
Anti-ARHGAP10 Antibody (CAB18492)
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- SKU:
- CAB18492
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-ARHGAP10 Antibody |
| Antibody SKU: | CAB18492 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human ARHGAP10. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: |
| Immunogen: | Recombinant protein of human ARHGAP10. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 79658 |
| Uniprot: | A1A4S6 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
| Synonyms: | GRAF2, PS-GAP, PSGAP, ARHGAP10 |
| Background: |
| UniProt Protein Function: | ARHGAP10: GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death. |
| UniProt Protein Details: | Protein type:GAPs, Rac/Rho; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 4q31.23 Cellular Component: cytosol Molecular Function:GTPase activator activity; protein binding Biological Process: regulation of small GTPase mediated signal transduction |
| UniProt Code: | A1A4S6 |
| NCBI GenInfo Identifier: | 158706193 |
| NCBI Gene ID: | 79658 |
| NCBI Accession: | A1A4S6.1 |
| UniProt Secondary Accession: | A1A4S6,Q2VPC4, Q2VPC5, Q96EV3, Q96S75, A1L0S5, |
| UniProt Related Accession: | A1A4S6 |
| Molecular Weight: | 89,375 Da |
| NCBI Full Name: | Rho GTPase-activating protein 10 |
| NCBI Synonym Full Names: | Rho GTPase activating protein 10 |
| NCBI Official Symbol: | ARHGAP10 |
| NCBI Official Synonym Symbols: | GRAF2; PSGAP; PS-GAP |
| NCBI Protein Information: | rho GTPase-activating protein 10 |
| UniProt Protein Name: | Rho GTPase-activating protein 10 |
| UniProt Synonym Protein Names: | GTPase regulator associated with focal adhesion kinase 2; Graf-related protein 2; Rho-type GTPase-activating protein 10 |
| Protein Family: | Rho GTPase-activating protein |
| UniProt Gene Name: | ARHGAP10 |
| UniProt Entry Name: | RHG10_HUMAN |
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