Cell Biology Antibodies 17

Anti-ARHGAP10 Antibody (CAB18492)

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SKU:
CAB18492
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-ARHGAP10 Antibody
Antibody SKU:CAB18492
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:Recombinant protein of human ARHGAP10.
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse
Positive Samples:
Immunogen:Recombinant protein of human ARHGAP10.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:79658
Uniprot:A1A4S6
Cellular Location:
Calculated MW:
Observed MW:Refer to figures
Synonyms:GRAF2, PS-GAP, PSGAP, ARHGAP10
Background:
UniProt Protein Function:ARHGAP10: GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death.
UniProt Protein Details:

Protein type:GAPs, Rac/Rho; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 4q31.23

Cellular Component: cytosol

Molecular Function:GTPase activator activity; protein binding

Biological Process: regulation of small GTPase mediated signal transduction

UniProt Code:A1A4S6
NCBI GenInfo Identifier:158706193
NCBI Gene ID:79658
NCBI Accession:A1A4S6.1
UniProt Secondary Accession:A1A4S6,Q2VPC4, Q2VPC5, Q96EV3, Q96S75, A1L0S5,
UniProt Related Accession:A1A4S6
Molecular Weight:89,375 Da
NCBI Full Name:Rho GTPase-activating protein 10
NCBI Synonym Full Names:Rho GTPase activating protein 10
NCBI Official Symbol:ARHGAP10  
NCBI Official Synonym Symbols:GRAF2; PSGAP; PS-GAP  
NCBI Protein Information:rho GTPase-activating protein 10
UniProt Protein Name:Rho GTPase-activating protein 10
UniProt Synonym Protein Names:GTPase regulator associated with focal adhesion kinase 2; Graf-related protein 2; Rho-type GTPase-activating protein 10
Protein Family:Rho GTPase-activating protein
UniProt Gene Name:ARHGAP10  
UniProt Entry Name:RHG10_HUMAN
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