Anti-ARF5 Antibody (CAB3382)

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SKU:
CAB3382
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

Product Name:ARF5 Rabbit mAb
Product Code:CAB3382
Size:20uL, 50uL, 100uL
Applications:WB, IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human ARF5
Applications:WB, IF
Recommended Dilutions:WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:HeLa, HepG2, Rat brain
Immunogen:A synthesized peptide derived from human ARF5
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:381
Uniprot:P84085
Calculated MW:18kDa
Observed MW:18kDa
UniProt Protein Function:ARF5: GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Belongs to the small GTPase superfamily. Arf family.
UniProt Protein Details:

Protein type:G protein, monomeric, ARF; G protein; G protein, monomeric; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 7q31.3

Cellular Component: Golgi apparatus; perinuclear region of cytoplasm; plasma membrane

Molecular Function:GTPase activity; protein binding; GTP binding

Biological Process: vesicle-mediated transport; protein transport; metabolic process; small GTPase mediated signal transduction

NCBI Summary:This gene is a member of the human ADP-ribosylation factor (ARF) gene family. These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 6 ARF proteins and 11 ARF-like proteins and constitute 1 family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2,and ARF3), class II (ARF4 and ARF5) and class III (ARF6). The members of each class share a common gene organization. [provided by RefSeq, Dec 2010]
UniProt Code:P84085
NCBI GenInfo Identifier:51316990
NCBI Gene ID:381
NCBI Accession:P84085.2
UniProt Secondary Accession:P84085,P26437,
UniProt Related Accession:P84085
Molecular Weight:180
NCBI Full Name:ADP-ribosylation factor 5
NCBI Synonym Full Names:ADP-ribosylation factor 5
NCBI Official Symbol:ARF5  
NCBI Protein Information:ADP-ribosylation factor 5
UniProt Protein Name:ADP-ribosylation factor 5
Protein Family:Auxin response factor
UniProt Gene Name:ARF5  
UniProt Entry Name:ARF5_HUMAN
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