Metabolism Antibodies 3
Anti-APC Antibody (CAB17912)
- SKU:
- CAB17912
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Description
| Antibody Name: | Anti-APC Rabbit Monoclonal Antibody |
| Antibody SKU: | CAB17912 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human APC |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | SW480, Mouse brain, Mouse lung, Rat brain |
| Immunogen: | A synthesized peptide derived from human APC |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 324 |
| Uniprot: | P25054 |
| Cellular Location: | |
| Calculated MW: | 160kDa |
| Observed MW: | 160kDa |
 | Western blot - APC Rabbit mAb (CAB17912) |
| Synonyms: | APC, BTPS2, DP2, DP2.5, DP3, GS, PPP1R46 |
| Background: | This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P25054 |
| NCBI GenInfo Identifier: | 97535708 |
| NCBI Gene ID: | 324 |
| NCBI Accession: | P25054.2 |
| UniProt Secondary Accession: | P25054,Q15162, Q15163, Q93042, D3DT03, |
| UniProt Related Accession: | P25054 |
| Molecular Weight: | 461 |
| NCBI Full Name: | Adenomatous polyposis coli protein |
| NCBI Synonym Full Names: | adenomatous polyposis coli |
| NCBI Official Symbol: | APC |
| NCBI Official Synonym Symbols: | GS; DP2; DP3; BTPS2; DP2.5; PPP1R46 |
| NCBI Protein Information: | adenomatous polyposis coli protein; deleted in polyposis 2.5; adenomatosis polyposis coli tumor suppressor; protein phosphatase 1, regulatory subunit 46 |
| UniProt Protein Name: | Adenomatous polyposis coli protein |
| UniProt Synonym Protein Names: | Deleted in polyposis 2.5 |
| Protein Family: | APC-related protein |
| UniProt Gene Name: | APC |
| UniProt Entry Name: | APC_HUMAN |
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