Cell Biology Antibodies 15
Anti-APBA1 Antibody (CAB18582)
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- SKU:
- CAB18582
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-APBA1 Antibody |
| Antibody SKU: | CAB18582 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | IHC IF |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human APBA1. |
| Application: | IHC IF |
| Recommended Dilution: | IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse |
| Positive Samples: |
| Immunogen: | Recombinant protein of human APBA1. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 320 |
| Uniprot: | Q02410 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
 | Immunohistochemistry - APBA1 Rabbit pAb (CAB18582) |
| Synonyms: | D9S411E, LIN10, MINT1, X11, X11A, X11ALPHA, APBA1 |
| Background: |
| UniProt Protein Function: | Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta. |
| NCBI Summary: | The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q02410 |
| NCBI GenInfo Identifier: | 22035548 |
| NCBI Gene ID: | 320 |
| NCBI Accession: | NP_001154.2 |
| UniProt Secondary Accession: | Q02410,O14914, O60570, Q5VYR8, |
| UniProt Related Accession: | Q02410 |
| Molecular Weight: | 91,594 Da |
| NCBI Full Name: | amyloid-beta A4 protein-binding family A member 1 |
| NCBI Synonym Full Names: | amyloid beta precursor protein binding family A member 1 |
| NCBI Official Symbol: | APBA1 |
| NCBI Official Synonym Symbols: | X11; X11A; LIN10; MINT1; D9S411E; X11ALPHA |
| NCBI Protein Information: | amyloid-beta A4 precursor protein-binding family A member 1 |
| UniProt Protein Name: | Amyloid-beta A4 precursor protein-binding family A member 1 |
| UniProt Synonym Protein Names: | Adapter protein X11alpha; Neuron-specific X11 protein; Neuronal Munc18-1-interacting protein 1; Mint-1 |
| Protein Family: | Amyloid beta A4 precursor protein-binding family |
| UniProt Gene Name: | APBA1 |
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