Cell Biology Antibodies 13

Anti-AP1G2 Antibody (CAB17582)

(No reviews yet) Write a Review
SKU:
CAB17582
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-AP1G2 Antibody
Antibody SKU:CAB17582
Antibody Size:20uL, 50 uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 260-360 of human AP1G2 (NP_001269404).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 260-360 of human AP1G2 (NP_001269404).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:SLLR LVQS DHSA VQRH RPTV VECL RETD ASLS RRAL ELSL ALVN SSNV RAMM QELQ AFLE SCPP DLRA DCAS GILL AAER FAPT KRWH IDTI LHVL TTAG T
Gene ID:8906
Uniprot:O75843
Cellular Location:
Calculated MW:87kDa
Observed MW:Refer to figures
Synonyms:AP1G2, G2AD
Background:Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is compsed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. This protein along with the complex is thought to function at some trafficking step in the complex pathways between the trans-Golgi network and the cell surface. Several alternatively spliced transcript variants of this gene exist, but their full-length nature is not known. [provided by RefSeq, Aug 2013]
UniProt Protein Function:AP1G2: May function in protein sorting in late endosomes or multivesucular bodies (MVBs). Involved in MVB-assisted maturation of hepatitis B virus (HBV). Belongs to the adaptor complexes large subunit family.
UniProt Protein Details:

Protein type:Adaptor/scaffold

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: AP-1 adaptor complex; Golgi apparatus; Golgi membrane; Golgi-associated vesicle; membrane; transport vesicle

Molecular Function:protein binding

NCBI Summary:Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is compsed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. This protein along with the complex is thought to function at some trafficking step in the complex pathways between the trans-Golgi network and the cell surface. Several alternatively spliced transcript variants of this gene exist, but their full-length nature is not known. [provided by RefSeq, Aug 2013]
UniProt Code:O75843
NCBI GenInfo Identifier:12643299
NCBI Gene ID:8906
NCBI Accession:O75843.1
UniProt Secondary Accession:O75843,O75504, D3DS51,
UniProt Related Accession:O75843
Molecular Weight:87,117 Da
NCBI Full Name:AP-1 complex subunit gamma-like 2
NCBI Synonym Full Names:adaptor related protein complex 1 gamma 2 subunit
NCBI Official Symbol:AP1G2  
NCBI Official Synonym Symbols:G2AD  
NCBI Protein Information:AP-1 complex subunit gamma-like 2
UniProt Protein Name:AP-1 complex subunit gamma-like 2
UniProt Synonym Protein Names:Gamma2-adaptin; G2ad
Protein Family:AP-1 complex
UniProt Gene Name:AP1G2  
UniProt Entry Name:AP1G2_HUMAN
View AllClose

0 Reviews

View AllClose

Related Products