Description
| Product Name: | AP1G1 Rabbit mAb |
| Product Code: | CAB19269 |
| Size: | 20uL, 50uL, 100uL |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human AP1G1. |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, 293T, HepG2, Mouse liver, Mouse brain, Rat liver, Rat brain |
| Immunogen: | Recombinant protein of human AP1G1. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 164 |
| Uniprot: | O43747 |
| Calculated MW: | 100kDa |
| Observed MW: | 100KDa |
| UniProt Protein Function: | Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. |
| UniProt Protein Details: | |
| NCBI Summary: | Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O43747 |
| NCBI GenInfo Identifier: | 71773010 |
| NCBI Gene ID: | 164 |
| NCBI Accession: | NP_001025178.1 |
| UniProt Secondary Accession: | O43747,O75709, O75842, Q9UG09, Q9Y3U4 |
| UniProt Related Accession: | O43747 |
| Molecular Weight: | 91,723 Da |
| NCBI Full Name: | AP-1 complex subunit gamma-1 isoform a |
| NCBI Synonym Full Names: | adaptor related protein complex 1 subunit gamma 1 |
| NCBI Official Symbol: | AP1G1 |
| NCBI Official Synonym Symbols: | ADTG; CLAPG1 |
| NCBI Protein Information: | AP-1 complex subunit gamma-1 |
| UniProt Protein Name: | AP-1 complex subunit gamma-1 |
| UniProt Synonym Protein Names: | Adaptor protein complex AP-1 subunit gamma-1; Adaptor-related protein complex 1 subunit gamma-1; Clathrin assembly protein complex 1 gamma-1 large chain; Gamma1-adaptin; Golgi adaptor HA1/AP1 adaptin subunit gamma-1 |
| Protein Family: | AP-1 complex |
| UniProt Gene Name: | AP1G1 |
| UniProt Entry Name: |