Cell Biology Antibodies 8
Anti-AOX1 Antibody (CAB3586)
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- SKU:
- CAB3586
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-AOX1 Antibody |
| Antibody SKU: | CAB3586 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 340-590 of human AOX1 (NP_001150.3). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | LO2, 293T, Mouse liver, Mouse pancreas, Rat liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 340-590 of human AOX1 (NP_001150.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | HLGT LAGS QIRN MASL GGHI ISRH PDSD LNPI LAVG NCTL NLLS KEGK RQIP LNEQ FLSK CPNA DLKP QEIL VSVN IPYS RKWE FVSA FRQA QRQE NALA IVNS GMRV FFGE GDGI IREL CISY GGVG PATI CAKN SCQK LIGR HWNE QMLD IACR LILN EVSL LGSA PGGK VEFK RTLI ISFL FKFY LEVS QILK KMDP VHYP SLAD KYES ALED LHSK HHCS TLKY QNIG PKQH PEDP IGHP IMHL SGV |
| Gene ID: | 316 |
| Uniprot: | Q06278 |
| Cellular Location: | Cytoplasm |
| Calculated MW: | 147kDa |
| Observed MW: | 180kDa |
| Synonyms: | AOX1, AO, AOH1 |
| Background: | Aldehyde oxidase produces hydrogen peroxide and, under certain conditions, can catalyze the formation of superoxide. Aldehyde oxidase is a candidate gene for amyotrophic lateral sclerosis. |
| UniProt Protein Function: | AOX1: Aldehyde oxidase produces hydrogen peroxide and, under certain conditions, can catalyze the formation of superoxide. Aldehyde oxidase is a candidate gene for amyotrophic lateral sclerosis. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Xenobiotic Metabolism - drug metabolism - cytochrome P450; EC 1.2.3.1; Cofactor and Vitamin Metabolism - vitamin B6; Amino Acid Metabolism - tyrosine; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; Amino Acid Metabolism - tryptophan; Oxidoreductase Chromosomal Location of Human Ortholog: 2q33 Cellular Component: cytoplasm; cytosol Molecular Function:aldehyde oxidase activity; FAD binding; xanthine dehydrogenase activity Biological Process: inflammatory response; vitamin B6 metabolic process; xanthine catabolic process |
| NCBI Summary: | Aldehyde oxidase produces hydrogen peroxide and, under certain conditions, can catalyze the formation of superoxide. Aldehyde oxidase is a candidate gene for amyotrophic lateral sclerosis. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q06278 |
| NCBI GenInfo Identifier: | 215273968 |
| NCBI Gene ID: | 316 |
| NCBI Accession: | Q06278.2 |
| UniProt Secondary Accession: | Q06278,O14765, Q53RR8, Q53TV3, Q9BYF0, Q9UPG6, |
| UniProt Related Accession: | Q06278 |
| Molecular Weight: | 147,918 Da |
| NCBI Full Name: | Aldehyde oxidase |
| NCBI Synonym Full Names: | aldehyde oxidase 1 |
| NCBI Official Symbol: | AOX1 |
| NCBI Official Synonym Symbols: | AO; AOH1 |
| NCBI Protein Information: | aldehyde oxidase |
| UniProt Protein Name: | Aldehyde oxidase |
| UniProt Synonym Protein Names: | Aldehyde oxidase 1; Azaheterocycle hydroxylase (EC:1.17.3.-) |
| Protein Family: | Alcohol oxidase |
| UniProt Gene Name: | AOX1 |
| UniProt Entry Name: | AOXA_HUMAN |
 | Western blot analysis of extracts of various cell lines, using AOX1 antibody (CAB3586) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
 | Immunofluorescence analysis of NIH/3T3 cells using AOX1 Rabbit pAb (CAB3586) at dilution of 1:100. Blue: DAPI for nuclear staining. |
 | Immunofluorescence analysis of HeLa cells using AOX1 Rabbit pAb (CAB3586) at dilution of 1:100. Blue: DAPI for nuclear staining. |
 | Immunofluorescence analysis of C6 cells using AOX1 Rabbit pAb (CAB3586) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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