Cell Biology Antibodies 11
Anti-ANXA8L2 Antibody (CAB7641)
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- SKU:
- CAB7641
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-ANXA8L2 Antibody |
| Antibody SKU: | CAB7641 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-276 of human ANXA8L2 (NP_001265853.1). |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | A-549, HeLa, Mouse lung, Mouse ovary |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-276 of human ANXA8L2 (NP_001265853.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MAWW KAWI EQEG VTVK SSSH FNPD PDAE TLYK AMKG IGVG SQLL SHQA AAFA FPSS ALTS VSPW GQQG HLCC NPAG TNEQ AIID VLTK RSNT QRQQ IAKS FKAQ FGKD LTET LKSE LSGK FERL IVAL MYPP YRYE AKEL HDAM KGSR DDVS SFVD PALA LQDA QDLY AAGE KIRG TDEM KFIT ILCT RSAT HLLR VKCT QNLH SYFA ERLY YAMK GAGT RDGT LIRN IVSR SEID LNLI KCHF KKMY GKTL SSMI MEDT SGDY KNAL LSLV GSDP |
| Gene ID: | 728113 |
| Uniprot: | Q5VT79 |
| Cellular Location: | |
| Calculated MW: | 30kDa/36kDa |
| Observed MW: | 37kDa |
| Synonyms: | ANXA8L1, ANXA8, ANXA8L2, VAC-beta, bA145E20.2 |
| Background: | This gene encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The encoded protein may function as an an anticoagulant that indirectly inhibits the thromboplastin-specific complex. Overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10. |
| UniProt Protein Function: | ANXA8L1: Belongs to the annexin family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 10q11.22 Molecular Function:calcium-dependent phospholipid binding; calcium ion binding |
| NCBI Summary: | This gene encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The encoded protein may function as an an anticoagulant that indirectly inhibits the thromboplastin-specific complex. Overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10. [provided by RefSeq, Apr 2014] |
| UniProt Code: | Q5VT79 |
| NCBI GenInfo Identifier: | 524552373 |
| NCBI Gene ID: | 728113 |
| NCBI Accession: | NP_001092315.2 |
| UniProt Secondary Accession: | Q5VT79,Q53FY2, Q5VT78, Q96H89, B2R939, |
| UniProt Related Accession: | Q5T2P8 |
| Molecular Weight: | 30,677 Da |
| NCBI Full Name: | annexin A8-like protein 1 isoform 1 |
| NCBI Synonym Full Names: | annexin A8-like 1 |
| NCBI Official Symbol: | ANXA8L1 |
| NCBI Official Synonym Symbols: | ANXA8; ANXA8L2; VAC-beta; bA145E20.2 |
| NCBI Protein Information: | annexin A8-like protein 1; annexin A8-like protein 2; annexin A8L2; annexin VIII; annexin-8; vascular anticoagulant-beta |
| UniProt Protein Name: | Annexin A8-like protein 2 |
| UniProt Gene Name: | ANXA8L2 |
| UniProt Entry Name: | AXA82_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ANXA8L2 antibody (CAB7641) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded rat kidney using ANXA8L2 antibody (CAB7641) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human prostate using ANXA8L2 antibody (CAB7641) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse brain using ANXA8L2 antibody (CAB7641) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse kidney using ANXA8L2 antibody (CAB7641) at dilution of 1:100 (40x lens). |
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