Description
| Product Name: | ANP32B Rabbit mAb |
| Product Code: | CAB3489 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | APRIL, PHAPI2, SSP29 |
| Applications: | WB, IHC, IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human ANP32B |
| Applications: | WB, IHC, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | A-549, PC-3, RAW264.7, U-937, Mouse testis |
| Immunogen: | A synthesized peptide derived from human ANP32B |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 10541 |
| Uniprot: | Q92688 |
| Cellular Location: | Cytoplasm, Nucleus |
| Calculated MW: | 29kDa |
| Observed MW: | 28-31kDa |
| UniProt Protein Function: | ANP32B: Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity. Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome. Belongs to the ANP32 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Chaperone Chromosomal Location of Human Ortholog: 9q22.32 Cellular Component: cytoplasm; nucleolus; nucleus Molecular Function:histone binding; protein binding Biological Process: caspase activation; negative regulation of cell differentiation; nucleosome assembly; positive regulation of protein export from nucleus |
| UniProt Code: | Q92688 |
| NCBI GenInfo Identifier: | 26390818 |
| NCBI Gene ID: | 10541 |
| NCBI Accession: | Q92688.1 |
| UniProt Secondary Accession: | Q92688,O00655, P78458, P78459, B2R9C7, |
| UniProt Related Accession: | Q92688 |
| Molecular Weight: | 22,277 Da |
| NCBI Full Name: | Acidic leucine-rich nuclear phosphoprotein 32 family member B |
| NCBI Synonym Full Names: | acidic nuclear phosphoprotein 32 family member B |
| NCBI Official Symbol: | ANP32B |
| NCBI Official Synonym Symbols: | APRIL; SSP29; PHAPI2 |
| NCBI Protein Information: | acidic leucine-rich nuclear phosphoprotein 32 family member B |
| UniProt Protein Name: | Acidic leucine-rich nuclear phosphoprotein 32 family member B |
| UniProt Synonym Protein Names: | Acidic protein rich in leucines; Putative HLA-DR-associated protein I-2; PHAPI2; Silver-stainable protein SSP29 |
| Protein Family: | Acidic leucine-rich nuclear phosphoprotein 32 family |
| UniProt Gene Name: | ANP32B |
| UniProt Entry Name: | AN32B_HUMAN |