Cell Biology Antibodies 17
Anti-ANAPC7 Antibody (CAB18459)
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- SKU:
- CAB18459
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-ANAPC7 Antibody |
| Antibody SKU: | CAB18459 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide of human ANAPC7. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: |
| Immunogen: | A synthetic peptide of human ANAPC7. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 51434 |
| Uniprot: | Q9UJX3 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
| Synonyms: | APC7, ANAPC7 |
| Background: |
| UniProt Protein Function: | Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. |
| NCBI Summary: | This gene encodes a tetratricopeptide repeat containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for proper protein ubiquitination function of APC/C and for the interaction of APC/C with certain transcription coactivators. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008] |
| UniProt Code: | Q9UJX3 |
| NCBI GenInfo Identifier: | 294862527 |
| NCBI Gene ID: | 51434 |
| NCBI Accession: | Q9UJX3.4 |
| UniProt Secondary Accession: | Q9UJX3,Q96AC4, Q96GF4, Q9BU24, Q9NT16, |
| UniProt Related Accession: | Q9UJX3 |
| Molecular Weight: | 67 kDa |
| NCBI Full Name: | Anaphase-promoting complex subunit 7 |
| NCBI Synonym Full Names: | anaphase promoting complex subunit 7 |
| NCBI Official Symbol: | ANAPC7 |
| NCBI Official Synonym Symbols: | APC7 |
| NCBI Protein Information: | anaphase-promoting complex subunit 7 |
| UniProt Protein Name: | Anaphase-promoting complex subunit 7 |
| UniProt Synonym Protein Names: | Cyclosome subunit 7 |
| Protein Family: | Anaphase-promoting complex |
| UniProt Gene Name: | ANAPC7 |
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