Cell Biology Antibodies 4
Anti-AMZ2 Antibody (CAB14333)
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- SKU:
- CAB14333
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-AMZ2 Antibody |
| Antibody SKU: | CAB14333 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 81-360 of human AMZ2 (NP_057711.3). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 81-360 of human AMZ2 (NP_057711.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | TPSP NKRS IYIQ SIGS LGNT RIIS EEYI KWLT GYCK AYFY GLRV KLLE PVPV SVTR CSFR VNEN THNL QIHA GDIL KFLK KKKP EDAF CVVG ITMI DLYP RDSW NFVF GQAS LTDG VGIF SFAR YGSD FYSM HYKG KVKK LKKT SSSD YSIF DNYY IPEI TSVL LLRS CKTL THEI GHIF GLRH CQWL ACLM QGSN HLEE ADRR PLNL CPIC LHKL QCAV GFSI VERY KALV RWID DESS DTPG ATPE HSHE DNGN LPKP VEAF KEWK EWII KCLA VLQK |
| Gene ID: | 51321 |
| Uniprot: | Q86W34 |
| Cellular Location: | |
| Calculated MW: | 34kDa/41kDa |
| Observed MW: | Refer to Figures |
| Synonyms: | AMZ2 |
| Background: | The protein encoded by this gene is a zinc metalloprotease that displays some activity against angiotensin-3. The encoded protein is inhibited by the aminopeptidase inhibitor amastatin, as well as by the general inhibitors o-phenanthroline and batimastat. Defects in this gene may be associated with lung tumorigenesis. |
| UniProt Protein Function: | AMZ2: Zinc metalloprotease. Exhibits activity against angiotensin-3 in vitro. Does not hydrolyze either neurogranin or angiotensin-2. Belongs to the peptidase M54 family. |
| UniProt Protein Details: | Protein type:Protease; EC 3.-.-.- Chromosomal Location of Human Ortholog: 17q24.2 Molecular Function:metallopeptidase activity; zinc ion binding Biological Process: proteolysis |
| UniProt Code: | Q86W34 |
| NCBI GenInfo Identifier: | 317373321 |
| NCBI Gene ID: | 51321 |
| NCBI Accession: | Q86W34.2 |
| UniProt Secondary Accession: | Q86W34,Q5XKF1, Q9NZE2, A6NLD9, B3KR44, |
| UniProt Related Accession: | Q86W34 |
| Molecular Weight: | 34,595 Da |
| NCBI Full Name: | Archaemetzincin-2 |
| NCBI Synonym Full Names: | archaelysin family metallopeptidase 2 |
| NCBI Official Symbol: | AMZ2 |
| NCBI Protein Information: | archaemetzincin-2; archaemetzincins-2; archeobacterial metalloproteinase-like protein 2 |
| UniProt Protein Name: | Archaemetzincin-2 |
| UniProt Synonym Protein Names: | Archeobacterial metalloproteinase-like protein 2 |
| Protein Family: | Archaemetzincin |
| UniProt Gene Name: | AMZ2 |
| UniProt Entry Name: | AMZ2_HUMAN |
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