Description
Antibody Name: | Anti-AMSH Antibody (CAB20889) |
Antibody SKU: | CAB20889 |
Antibody Size: | 50µL, 100µL |
Application: | Western blotting |
Reactivity: | Human, Monkey |
Host Species: | Rabbit |
Immunogen: | Recombinant protein of Human AMSH. |
Application: | Western blotting |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Human, Monkey |
Positive Samples: | 293T, HeLa, Jurkat, COS-7 |
Immunogen: | Recombinant protein of Human AMSH. |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Cellular Location: | Cytoplasm, Early endosome, Membrane, Nucleus, Peripheral membrane protein |
Calculated MW: | 39kDa/48kDa |
Observed MW: | 50KDa |
Synonyms: | STAMBP, AMSH, MICCAP |
Background: | Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. |
![]() | Western blot analysis of extracts of various cell lines, using AMSH antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s. |